P-menthane-3,8-diol |
Last updated: 12/06/2024
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(Also known as: PMD; para-menthane-3,8-diol; oil of lemon Eucalyptus; Eucalyptus citriodora crystals; Quwenling) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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Botanical substance and used topically as an insect repellent |
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Various flying insects including mosquitoes, gnats and black flies |
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Humans |
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Current |
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1997, introduced USA |
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- |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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A total of eight stereoisomers are possible, based on the three stereocenters of the ring. |
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C₁₀H₁₀O₂ |
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CC1CCC(C(C1)O)C(C)(C)O |
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- |
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LMXFTMYMHGYJEI-UHFFFAOYSA-N |
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InChI=1S/C10H20O2/c1-7-4-5-8(9(11)6-7)10(2,3)12/h7-9,11-12H,4-6H2,1-3H3 |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
p-menthane-3,8-diol |
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Insecticide, Semiochemical |
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Plant-derived substance |
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>28% |
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Natural |
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Repels biting insects by blocking or interfering with the receptor sites used in the host |
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Occurs naturally in the oil within leaves of the Eucalyptus citriodora tree |
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Extracted from Lemon Eucalyptus leaves or chemically synthesised for commercial use by a Prins reaction of citronellal |
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Public health applications |
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Various flying insects including mosquitoes, gnats and black flies |
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- |
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Not normally used in agricultural production |
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42822-86-6 |
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255-953-7 |
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- |
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011550 |
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556998 |
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162.2 |
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- |
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2-(1-hydroxy-1-methylethyl)-5-methylcyclohexanol |
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2-hydroxy-α,α,4-trimethylcyclohexanemethanol |
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- |
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- |
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Not applicable |
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Not applicable |
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Not known |
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Not applicable |
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- |
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Colourless liquid with faint minty odour |
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Mosi-Guard Natural |
Mosi-Guard International |
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Usually formulated as a liquid in sprays and roll-on products |
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290 |
at 25 °C |
Moderate |
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100000 |
Ethanol |
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100000 |
Ethylene glycol |
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100000 |
Isopropanol |
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34.5 |
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0.99 |
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181 |
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Highly volatile. If applied directly to plants or soil, drift is a concern & mitigation is advisable |
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4.34 X 10-05 |
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Non-volatile |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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> 5000 |
Rat |
Low |
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Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source No adverse effects identified or expected. |
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Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source No adverse effects identified or expected |
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Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source No adverse effects identified or expected. |
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HUMAN HEALTH AND PROTECTION |
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High (class III) |
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> 5000 |
Rat |
Low |
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5000 |
Rat |
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2.17 |
Rat |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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No adverse health effects noted except those of possible skin and eye irritation |
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No information available |
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Not listed (Not listed) |
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p-menthane-3,8-diol |
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Record last updated: |
12/06/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |