Streptomycin sulphate |
Last updated: 22/08/2024 |
(Also known as: Streptomycin sesquisulfate; Streptomycin A1; phytomycin; streptomycin sulfate; crop antibiotic) |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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Streptomycin is used to combat the growth of bacteria, fungi, and algae on fruit and vegetable crops. It also has applications as a drug specifically as a bactericidal antibiotic. | |
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Bacterial shot-hole; Bacterial rots; Bacterial canker; Bacterial wilts; Fire blight; Crown gall; Wildfire Blue mold | |
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Fruit including apples, pears, stone fruit, citrus; Olives; Vegetables including beans, peppers; Potatoes; Celery; Tobacco; Greenhouse crops; Cotton; Ornamentals; Plant cuttings | |
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UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes as streptomycin | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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USA |
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Chemical structure |
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Streptomycin sulphate is a chiral molecule | |
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CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O | |
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C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O | |
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QTENRWWVYAAPBI-YCRXJPFRSA-N | |
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InChI=1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1 | |
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Yes |
General status |
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Fungicide, Veterinary substance, Other substance | |
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Bactericide | |
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Micro-organism derived substance | |
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Natural | |
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A aminoglycoside that inhibites protein biosynthesis bybinding to the 30S subunit of the bacterial ribosome, systemic action | |
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Streptomycin sulphate is a water-soluble antibiotic originally purified from Streptomyces griseus. | |
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Crop protection | |
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Bacterial shot-hole; Bacterial rots; Bacterial canker; Bacterial wilts; Fire blight; Crown gall; Wildfire Blue mold | |
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Fruit including apples, pears, stone fruit, citrus; Olives; Vegetables including beans, peppers; Potatoes; Celery; Tobacco; Greenhouse crops; Cotton; Ornamentals; Plant cuttings | |
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3810-74-0 | |
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223-286-0 | |
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1457.4 | |
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2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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BM02 | |
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White to pale yellow hydroscopic powder with meal-like odour |
Formulations |
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Agri-Mycin 17 | NuFarm Inc., USA | ||||
Ferti-Lome Fire Blight Spray | Ferti-Lome, USA | |||||
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100,000 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 9000 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
Low | ||||||||
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> 4640 | E4 E = Manufacturers safety data sheets Anas platyrhynchos4 = Verified data |
Low | ||||||||
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> 100 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Apis mellifera3 = Unverified data of known source |
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Aquatic ecotoxicology |
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> 180 | E3 E = Manufacturers safety data sheets Oncorhynchus mykiss3 = Unverified data of known source |
Low | ||||||||
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650 | E3 E = Manufacturers safety data sheets Daphnia magna3 = Unverified data of known source |
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General |
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High (class III) | - | - | ||||||||
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> 9000 | E4 E = Manufacturers safety data sheets Rat4 = Verified data |
Low | ||||||||
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600 | E3 E = Manufacturers safety data sheets Rat3 = Unverified data of known source |
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Subcutaneous LD₅₀ = 500 mg kg⁻¹ | R3 R = Peer reviewed scientific publications Mouse3 = Unverified data of known source |
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Intravenous LD₅₀ = 90.2 mg kg⁻¹ | R3 R = Peer reviewed scientific publications Mouse3 = Unverified data of known source |
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Poorly and irregularly absorbed form the gastrointestinal tract. | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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No further information available |
Handling issues |
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Incompatible with strong oxidizing agents | |||
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Not listed (Not listed) | |||
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streptomycin sulphate | ||
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Record last updated: | 22/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |