Erwinia amylovora HrpN harpin protein |
Last updated: 12/06/2024
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(Also known as: Harpin protein) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A naturally occurring protein that can be used to control a wide range of viral, bacterial and fungal plant diseases. Also helps to reduce populations of certain insect pests. |
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Fire blight (Erwinia), Sheath blight (Rhizoctonia), Bacterial leaf blight (Xanthomonas), Citrus scab (Elsinoe fawcetti) and Leaf spot (Cercosporidium); Wilts; Shealth blight; Root-knot nematode; Tobacco mosaic virus |
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Soft and top fruit; Vegetables; Root crops; Potatoes; Tobacco; Hops; Essential oil crops; Ornamentals; Trees; Rice; Turf |
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Current |
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2002, full registration in USA |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Fungicide, Insecticide, Other substance |
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Bactericide |
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Micro-organism |
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Natural |
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It acts by eliciting a complex natural defense mechanism (hypersensitive Response) in plants analogous to a broad spectrum immune response in animals |
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A protein produced by the plant as a defence mechanism against Erwinia amylovora, a bacterium that causes fire blight |
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A weakened strain of Escherichia coli is modified to produce Harpin on a commercial scale |
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Crop protection; Increased yield |
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Fire blight (Erwinia), Sheath blight (Rhizoctonia), Bacterial leaf blight (Xanthomonas), Citrus scab (Elsinoe fawcetti) and Leaf spot (Cercosporidium); Wilts; Shealth blight; Root-knot nematode; Tobacco mosaic virus |
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Soft and top fruit; Vegetables; Root crops; Potatoes; Tobacco; Hops; Essential oil crops; Ornamentals; Trees; Rice; Turf |
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006477 |
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Erwinia amylovora HrpN harpin protein |
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Not applicable |
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Not applicable |
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Not known |
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BM02 |
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Micro-organism |
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Messenger |
Eden Bioscience |
Halo plant feed |
HydroGarden Wholesale Supplies Ltd |
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Usually supplied as water dispersible granules applied as a pre-plant or foliar spray with conventional ground or aerial spray equipment. |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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> 5000 |
Rat |
Low |
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> 4000 |
Colinus virginianus as product |
Low |
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No adverse effects identified or expected |
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Non-toxic |
No adverse effects identified or expected. |
Non-toxic |
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> 3720 |
Oncorhynchus mykiss as product |
Low |
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1173 |
Daphnia magna |
Low |
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> 182 |
Green algae as product |
Low |
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HUMAN HEALTH AND PROTECTION |
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Not applicable |
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> 5000 |
Rat |
Low |
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6000 |
Rat |
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> 2.0 |
Rat |
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Negligible risk to bystanders and consumers |
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Negligible risk to farm workers |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative |
XNo, known not to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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XNo, known not to cause a problem |
No data found |
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No adverse health effects reported or known |
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No information available |
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Not listed (Not listed) |
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Erwinia amylovora HrpN harpin protein |
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Record last updated: |
12/06/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |