Tenuazonic acid |
Last updated: 24/07/2024
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(Also known as: TeA) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A naturally occuring mycotoxin that is showing potential as a herbicide exibiting broad spectrum, rapid activity. |
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Croftonweed (Ageratina adenophora); Crabgrass; Barnyard grass; Pigweed |
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Cotton; Tobacco |
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Novel; Not yet commercially produced |
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1957, first isolated; 1990s, first examined for phytoxicity |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Patented in China & Japan |
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Herbicide |
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Micro-organism derived substance |
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Natural |
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Blocks electron transport beyond QA by interacting with D1 protein. PSII inhibitor resulting in plant cell death and plant necrosis. |
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A mycotoxin produced by members of the genus Alternaria and other phytopathogenic fungi |
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Crop protection |
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Croftonweed (Ageratina adenophora); Crabgrass; Barnyard grass; Pigweed |
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Cotton; Tobacco |
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610-88-8 |
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197.23 |
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(5S)-3-acetyl-5[(2S)-butan-2-yl]-4-hydroxy-1,5-dihydro-1H-pyrrol-2-one |
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Not known |
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Not known |
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Not applicable |
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Not applicable |
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White crystalline powder |
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3.5 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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3.2 |
R4 R = Peer reviewed scientific publications 4 = Verified data |
Non-persistent |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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200 |
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source Rat as natural form |
Moderate |
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HUMAN HEALTH AND PROTECTION |
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200 |
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source Rat as natural form |
Moderate |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
?Possibly, status not identified |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
Eye irritant |
Phototoxicant |
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?Possibly, status not identified |
No data found |
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Potentially beneficial - exhibits antitumor, antiviral and antibiotic activity May cause haemorrhage at high dose |
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Avoid contact with strong oxidising agents Will release toxic gases during combustion IMDG Transport Hazard Class 6.1 |
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Health: H301, H315, H319, H361, H335 |
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Not listed (Not listed) |
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UN2811 |
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Packaging Group II (moderate danger) |
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tenuazonic acid |
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Record last updated: |
24/07/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |