Carvacrol |
Last updated: 24/07/2024
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(Also known as: cymophenol) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A naturally occurring plant phenol which has numerous applications as an insecticide, antimicrobial and as an external animal parasite repellent |
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Houseflies; Cockroaches; Varroa mite |
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Bee hives; Public places; Domestic households |
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Current |
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- |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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None |
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C₁₀H₁₄O |
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CC1=C(C=C(C=C1)C(C)C)O |
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- |
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RECUKUPTGUEGMW-UHFFFAOYSA-N |
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InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3 |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
dicarvacrol |
Variant |
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Insecticide, Acaricide, Veterinary substance, Semiochemical, Fungicide |
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Antimicrobial |
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Plant-dervived substance |
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- |
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Natural |
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Multiple modes of action: carvacrol is a neurotoxin, antagonist of GABA and Acetylcholinesterase (AchE) inhibitor. |
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Carvacrol is a botanical chemical which occurs in high concentrations in oregano and thyme |
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Carvacrol may be produced via several methods including: (1) desulfonation, (2) diazotization, (3) prolonged heating of camphor and iodine, (4) dehydrogenation and (5) transalkylation of isopropylated cresols |
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Public health, Veterinary; Honey bee welfare |
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Houseflies; Cockroaches; Varroa mite |
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Bee hives; Public places; Domestic households |
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- |
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499-75-2 |
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207-889-6 |
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- |
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- |
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10364 |
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150.22 |
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2-methyl-5-(propan-2-yl)phenol |
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2-methyl-5-(propan-2-yl)benzenol |
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5-Isopropyl-2-methylphenol |
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FEMA=2245 |
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- |
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Not applicable |
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Not applicable |
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Not known |
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- |
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Colourless to pale yellow, viscous liquid with a pungent, spicy odour |
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125 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
Moderate |
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1.0 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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238 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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100 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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3.09 X 1003 |
Calculated |
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3.49 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
High |
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0.976 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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810 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
Moderate |
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HUMAN HEALTH AND PROTECTION |
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810 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
Moderate |
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2700 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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No data found |
XNo, known not to cause a problem |
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Carvacrol is not a substance of toxicological concern Possible anticarcinogen |
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Corrosive Extinguish fires with foam, dry extinguishing powder, carbon dioxide (CO2), water spray jet May emit toxic fumes in a fire Not compatible with strong oxidizers IMDG Transport Hazard Class 8 |
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Health: H302, H314 Environment: H411 |
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Not listed (Not listed) |
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UN3265 |
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Packaging Group III (minor danger) |
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carvacrol |
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Record last updated: |
24/07/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |