Antoferine |

Last updated: 25/08/2025
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(Not known by any other names) |
This is a plant derived fungicide for which little data is currently available. The substance is not yet commercially available and is currently subject to regulatory risk assessment. |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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A natural antifungal agent comprised of a polyphenols, including trans-resveratrol, trans-ɛ-viniferin, and vitisine, produced from vineyard wood waste using an eco-extraction process |
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Apple scab, Downy mildew, Late blight, Fusarium wilt, Potato late blight |
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Top fruit; Grapes; Potatoes; Wheat; Bananas |
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Not approved |
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Not applicable |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Malta |
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- |
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Not applicable |
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Pending |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Fungicide |
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Plant-derived substance |
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Natural |
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Biomimicry - antoferine is comprised of various plant phytoalexins |
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A natural antifungal agent comprised of a polyphenols, including trans-resveratrol, trans-ɛ-viniferin, and vitisine, produced from vineyard wood waste |
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Crop protection |
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Apple scab, Downy mildew, Late blight, Fusarium wilt, Potato late blight |
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Top fruit; Grapes; Potatoes; Wheat; Bananas |
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antoferine |
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Not applicable |
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Not applicable |
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Not applicable |
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Not known |
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Liquid |
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Novel |
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2014, first discovered France |
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Usually formulated as a wettable powder |
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Antoferine is produced through an innovative, eco-friendly extraction using vineyard by-products such as vine wood. Instead of relying on chemical solvents, the method employs industrial-scale microwave technology at 915 MHz to release bioactive polyphenols by heating and pressurising plant cells internally. |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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HUMAN HEALTH AND PROTECTION |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
No data found |
No data found |
Eye irritant |
Phototoxicant |
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No data found |
No data found |
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No information available |
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No information available |
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antoferine |
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Record last updated: |
25/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |