Pyraclonil (Ref: NAI-1886) |
Last updated: 24/07/2024 |
(Not known by any other names) |
SUMMARY |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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Warning: Significant data are missing |
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A herbicide used for preemergence and early post emergence control of weeds in rice crops | |
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Water hyacinth (Monochoria vaginalis); Chinese arrowhead (Sagittaria triflolia); Sedges; Barnyardgrass; Watergrass | |
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Paddy rice | |
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- | |
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2007, first registered |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Japan, USA |
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Chemical structure |
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None | |
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C₁₅H₁₅ClN₆ | |
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CN(CC#C)C1=C(C=NN1C2=NN3CCCCC3=C2Cl)C#N | |
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- | |
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IHHMUBRVTJMLQO-UHFFFAOYSA-N | |
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InChI=1S/C15H15ClN6/c1-3-7-20(2)15-11(9-17)10-18-22(15)14-13(16)12-6-4-5-8-21(12)19-14/h1,10H,4-8H2,2H3 | |
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Yes |
General status |
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Herbicide | |
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Nitrile herbicide; Pyrazole herbicide | |
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>98% | |
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- | |
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Synthetic | |
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Broad spectrum. Inhibition of protoporphyrinogen oxidase (PPO) - cell membrane disruption | |
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158353-15-2 | |
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805-557-0 | |
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None allocated | |
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- | |
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11563984 | |
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No data found | |
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314.77 | |
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1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-5-[methyl(prop-2-yn-1-yl)amino]-1H-pyrazole-4-carbonitrile | |
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1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-5-[methyl(prop-2-ynyl)amino]pyrazole-4-carbonitrile | |
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1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-5-(methyl-2-propynylamino)-1H-pyrazole-4-carbonitrile | |
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- | |
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- | |
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E | |
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14 | |
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Not applicable | |
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Not applicable | |
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- | |
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- |
Formulations |
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Usually formulated as granules. Where approved, it may be applied aerially. |
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50.1 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Moderate | ||||||||
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1.51 X 1002 | Calculated | - | |||||||
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2.18 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low | ||||||||
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1.34 | Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
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- | |||||||||||
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7.1 X 10-03 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low volatility | ||||||||
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1.2 X 10-11 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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44 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Moderately persistent | |||||||
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44 | P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source |
Moderately persistent | ||||||||
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US EPA data: Lab studies DT₅₀ values ranging from 8.4 – 76 days under aerobic conditions | ||||||||||
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104 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Stable | |||||||
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Corrected for summer sunlight at 35 N | ||||||||||
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Stable | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Stable | |||||||
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Stable at pH 4, 7 and 9 | ||||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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7.6 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Moderately mobile | |||||||
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345 | ||||||||||
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US EPA data Kf range 2.24-15.2 mL g⁻¹, Koc range 163-733 mL g⁻¹, Soils =10 | ||||||||||
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Fate indices |
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2.40 | Calculated | Transition state | ||||||||||||||||||||||||||
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1.33 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Moderately mobile | Calculated | - | ||||||||||||||||||||||||||
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Low risk | Q3 Q = Miscellaneous data from online sources Based on LogP < 33 = Unverified data of known source |
Low risk | |||||||||||||||||||||||||
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Known soil metabolites |
None
Known groundwater metabolites |
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Unknown relevancy | - | - | ||||||
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Unknown relevancy | - | - | ||||||
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Unknown relevancy | - | - |
Other known metabolites |
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1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methylamino)-1H-pyrazole-4-carbonitrile Note: US EPA data |
pyraclonil M-1 | Aqueous photolysis | >0.100 | ||||
1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methyl(prop-2-enyl)amino)-1H-pyrazole-4-carbonitrile Note: US EPA data |
pyraclonil M-11 | Surface water | >0.100 | ||||
1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methylamino)-1H-pyrazole-4-carboxamide Note: US EPA data |
pyraclonil M-6 | Surface water | >0.100 | ||||
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-1H-pyrazole-4-carboxamide Note: US EPA data |
pyraclonil M-7a | Surface water | <0.100 | ||||
1-(3-chloro-4-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methylamino)-1H-pyrazole-4-carbonitrile Note: US EPA data |
pyraclonil M-7b | Aqueous photolysis | <0.100 | ||||
N-(1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-4-cyano-1H-pyrazol-5-yl)-N-methylformamide Note: US EPA data |
pyraclonil methylformamide | Surface water | <0.100 | ||||
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-1H-pyrazole-4-carbonitrile Note: US EPA data |
- | Surface water | <0.100 | ||||
11-(3-chloro-4-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methyl(prop-2-yn-1-yl)amino)-1H-pyrazole-4-carbonitrile Note: US EPA data |
4-hydroxy-pyraclonil | Surface water | <0.100 | ||||
4-(4'-chloro-4-cyano-5-(methylamino)-1'H-[1,3'-bipyrazol]-5'-yl)butanoic acid Note: US EPA data |
pyraclonil VIII | Surface water | <0.100 | ||||
1-(3-chloro-4-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-alpha]pyridin-2-yl)-5-(methylamino)-1H-pyrazole-4-carbonitrile Note: US EPA data |
pyraclonil PM-5 | Surface water | <0.100 |
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Terrestrial ecotoxicology |
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> 877 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Mouse4 = Verified data |
Moderate | ||||||||
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> 2160 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Colinus virginianus4 = Verified data |
Low | ||||||||
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> 100 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Apis mellifera4 = Verified data |
Low | |||||||
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> 44.0 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Apis mellifera4 = Verified data |
Moderate | ||||||||
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Aquatic ecotoxicology |
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6.0 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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23.05 | R4 R = Peer reviewed scientific publications Danio rerio4 = Verified data |
Moderate | ||||||||
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15.09 | R4 R = Peer reviewed scientific publications Daphnia magna4 = Verified data |
Moderate | ||||||||
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0.0062 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Lemna minor4 = Verified data |
High | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 877 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Mouse4 = Verified data |
Moderate | ||||||||
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Not expected to be hazardous to residents or bystanders when used as directed | |||||||||
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Health issues |
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Possible liver and thyroid toxicant EPA data: Likely to be Carcinogenic to Humans |
Handling issues |
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No information available | |||
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Health: H302, H315, H319, H335 Environment: H400 |
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Not listed (Not listed) | |||
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pyraclonil | ||
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Record last updated: | 24/07/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |