Alpha-chlorohydrin (Ref: U 5897) |
Last updated: 02/06/2024 |
(Also known as: alpha,gamma-dichlorohydrin; 1,3-DCP; ACH) |
SUMMARY |
Alpha-chlorohydrin is a rodenticide that is not generally approved for use in the developed world. It has high potential for bio-concentration, moderately toxic to mammals, an eye irritant and a neurotoxin. Alpha-chlorohydrin is highly soluble in water and volatile but there is little environmental fate data available. It is highly toxic to birds but less toxic to fish. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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Warning: Significant data are missing |
Warning: Significant data are missing |
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A restricted use rodenticide for the specific control of Norwegian rats in indoor situations | |
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Norwegian rats | |
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Current | |
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1991, first registered USA |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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USA |
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Chemical structure |
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Alpha-chlorohydrin is a chiral molecule. The technical material is an isomeric mixture of the S- and R- optical isomers. | |
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C₃H₇ClO₂ | |
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C(C(CCl)O)O | |
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No data | |
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SSZWWUDQMAHNAQ-UHFFFAOYSA-N | |
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InChI=1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2 | |
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Yes |
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Common Name | Relationship | Link |
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chlorohydrin | Unstated isomer |
General status |
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Rodenticide, Other substance | |
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Chemiosterilant | |
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Organochloride rodenticide | |
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Synthetic | |
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Distrupts the reproduction ability of male rats | |
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96-24-2 | |
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202-492-4 | |
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None allocated | |
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117101 | |
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7290 | |
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No data found | |
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110.54 | |
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3-chloro-1,2-dihydroxypropane | |
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3-chloro-1,2-propanediol | |
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PAN Bad Actor Chemical | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Viscous colourless liquid |
Formulations |
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Available as placeable bait packages for usse in tamper-resistance stations. Product contains 1% of the active substance. |
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100000 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
High | ||||||||
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-40 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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Decomposes before boiling | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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213 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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1.41 X 10-01 | Calculated | - | |||||||
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-0.85 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | ||||||||
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Likely to be Soluble | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Based on chemical group | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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1.322 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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13.0 X 10-05 | F2 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 2 = Unverified data of unknown source |
Low volatility | ||||||||
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6.18 X 10-03 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | V1 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 1 = Estimated data with little or no verification |
Very mobile | |||||||
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1.0 | ||||||||||
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Estimated | ||||||||||
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Fate indices |
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Cannot be calculated | - | - | |||||||||||||||||||||||||
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Likely to be soluble | - |
Known metabolites |
None
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Terrestrial ecotoxicology |
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131 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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23.7 | V2 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Unknown species2 = Unverified data of unknown source |
High | ||||||||
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Aquatic ecotoxicology |
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2150 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rasbora heteromorpha3 = Unverified data of known source |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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131 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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2000 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat3 = Unverified data of known source |
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4.0 | R3 R = Peer reviewed scientific publications Rat 4 hr3 = Unverified data of known source |
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List II | - | - | ||||||||
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Health issues |
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Moderately toxic May cause pulmonary hemorrhaging & congestion Kidney and liver toxicant CLP data - suspected carcinogen |
Handling issues |
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Corrosive | |||
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Handling: H290 Health: H301, H315, H318, H330, H351 |
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Ib (Highly hazardous) | |||
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alpha-chlorohydrin | ||
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Record last updated: | 02/06/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |