Chlorothalonil (Ref: DS 2787) |
Last updated: 22/08/2024 |
(Also known as: TPN; tetrachloroisophthalonitrile; m-TCPN; HSR002825) |
SUMMARY |
Chlorothalonil is a broad-spectrum fungicide. It has a low aqueous solubility, is volatile and would not be expected to leach to groundwater. It is slightly mobile. It tends not to be persistent in soil systems but may be persistent in water. It has a low mammalian toxicity but there is some concern regarding its bioaccumulation potential. It is a recognised irritant. Chlorothalonil is moderately toxic to birds, honeybees and earthworms but considered to be more toxic to aquatic organisms. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A fungicide used to control a wide range of diseases on a broad range of crops. Also used as a wood preservative. | |
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Rust; purple spot; Leaf blight; Anthracnose; Downy mildew; Ring spot; Stalk rot; Botrytis rot; Pod & stem blight | |
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Cereals; Vegetables including asparagus, beans, cabbage, cauliflower, broccoli, carrot, onions, celery, curcubits; Corn for seed; Fruit including cranberries, melon; Mushrooms; Peanuts; Potatoes | |
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Can be product specific but generally - Wheat/Mildew=Low; Wheat/Septori tritici=High; Barley/Rhynchosporium=Low; Barley/Ramularia=Moderate | |
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Current | |
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1964, first reported |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Netherlands/Belgium | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Australia, USA |
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Chemical structure |
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None | |
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C₈Cl₄N₂ | |
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C(#N)C1=C(C(=C(C(=C1Cl)Cl)Cl)C#N)Cl | |
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No data | |
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CRQQGFGUEAVUIL-UHFFFAOYSA-N | |
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InChI=1S/C8Cl4N2/c9-5-3(1-13)6(10)8(12)7(11)4(5)2-14 | |
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Yes |
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Common Name | Relationship | Link |
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chlorothalonil | - |
General status |
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Fungicide | |
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Chloronitrile fungicide; Nitrile fungicide | |
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985 g kg⁻¹ | |
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EU dossier - Hexachlorobenzene 0.04 g kg⁻¹; Decachlorobiphenyl 0.03 g kg⁻¹ | |
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Synthetic | |
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Non-systemic, broad-spectrum, foliar action with some protectant properties. Acts by preventing spore germination and zoospore motility. Multi-site activity. | |
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1897-45-6 | |
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217-588-1 | |
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288 | |
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081901 | |
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15910 | |
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608-014-00-4 | |
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265.91 | |
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2,4,5,6-tetrachlorobenzene-1,3-dicarbonitrile | |
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tetrachloroisophthalonitrile | |
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2,4,5,6-tetrachloro-1,3-benzenedicarbonitrile | |
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Currently being phased out in EU; PAN Bad Actor Chemical | |
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UK Environment Agency non-statutory standard for the protection of aquatic life: freshwater and saltwater annual average 0.1 µg l⁻¹, max acceptable conc 1.0 µg l⁻¹ | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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M05 | |
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- | |
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White crystalline solid at 99.6% purity |
Formulations |
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Usually supplied as a soluble concentrate that is mixed with water and applied as a foliar spray |
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0.81 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 25°C5 = Verified data used for regulatory purposes |
Low | ||||||||
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13800 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | ||||||||
18000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone at 25°C5 = Verified data used for regulatory purposes |
- | |||||||||
1700 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Methanol at 25°C5 = Verified data used for regulatory purposes |
- | |||||||||
74400 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Xylene5 = Verified data used for regulatory purposes |
- | |||||||||
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252.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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347 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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347 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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8.71 X 1002 | Calculated | - | |||||||
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2.94 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Insoluble | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 4 = Verified data |
- | |||||||
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Regulatory data | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 4 = Verified data |
- | ||||||||
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1.74 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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Not applicable | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
No dissociation | |||||||||||
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0.076 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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2.50 X 10-02 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-volatile | ||||||||
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- | - | - | ||||||||
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232nm = 62390, 312nm = 1116, 324nm = 1507 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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71.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 21.5 °C 99.8%5 = Verified data used for regulatory purposes |
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Degradation |
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Not readily biodegradable | ||||||||||
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3.53 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | |||||||
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3.53 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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17.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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24.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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59.5 | - | - | ||||||||
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4.29 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) geometric mean of lab studies5 = Verified data used for regulatory purposes |
- | ||||||||
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EU dossier 2018: lab studies DT₅₀ range 0.256-19.0 days, DT₉₀ range 1.46-68.2 days, Soils=18; field studies DT₅₀ range 7.44-28.4 days, DT₉₀ range 24.7-94.2 days; Other sources: 30 days (DW3) | ||||||||||
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5.5 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 3.0-12.5 days, 8 field & undercover grown crops, various matrices, n=11 | ||||||||||
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5.0 | R4 R = Peer reviewed scientific publications 4 = Verified data |
- | |||||||
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Published literature RL₅₀ range 1.7-12.7 days, 11 field & undercover grown crops, various matrices, n=21 | ||||||||||
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0.72 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 4 = Verified data |
Fast | |||||||
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In sterile buffer | ||||||||||
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29.6 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 50 °C4 = Verified data |
Non-persistent | |||||||
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Stable pH 4 to pH 7 | ||||||||||
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0.57 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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0.82 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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- |
Soil adsorption and mobility |
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42.99 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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2632 | ||||||||||
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EU dossier RAR 2016; Kd range 7.7-153 mL g⁻¹, Koc range 300-6154 mL g⁻¹, Soils=9 | ||||||||||
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27.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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1288 | ||||||||||
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0.90 | ||||||||||
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EU RAR 2016: Kf range 3.0-74.1 mL g⁻¹, Kfoc range 330-7000 mL g⁻¹, 1/n range 0.83-0.95, Soils=12; Literature data: Kf range 96.3-1357 mL g⁻¹, Kfoc range 13462-52585 mL g⁻¹, 1/n range 0.48-0.69, Soils=8 | ||||||||||
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None |
Fate indices |
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1.12 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2.05 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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- | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Slightly mobile | Calculated | - | ||||||||||||||||||||||||||
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41172 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method4 = Verified data |
Substance of concern for long-range air transport | ||||||||||||||||||||||||||
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100 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Threshold for concern | |||||||||||||||||||||||||
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5 | - |
Known soil metabolites |
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Major fraction | 0.132 | - | |||||
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Major fraction | 0.124 | - | |||||
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Minor fraction | 0.060 | - | |||||
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Major fraction | 0.119 | - | |||||
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Minor fraction | 0.058 | - | |||||
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Minor fraction | 0.081 | - | |||||
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Major fraction | 0.132 | - | |||||
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Minor fraction | 0.065 | - | |||||
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Major fraction | 0.104 | - | |||||
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Major fraction | 0.322 | - | |||||
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Major fraction | 0.152 | - |
Known groundwater metabolites |
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Not relevant | - | - | ||||||
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Relevant | - | - | ||||||
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Relevant | - | - | ||||||
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Relevant | - | - | ||||||
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Relevant | - | - | ||||||
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Relevant | - | - | ||||||
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Relevant | - | - |
Other known metabolites |
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2-acetamido-3-[3-(2-acetamido-3-hydroxy-3-oxopropyl)sulfanyl-2,5-dichloro-4,6-dicyano-phenyl]sulfanylpropanoic acid (Ref: R613823) | - | Rat | - | ||||
2,5 dichloro-4,6 dicyano-benzene-1,3 disulfonic acid (Ref: R418503) | - | Crop | - | ||||
2-acetamido-3-[3,5-bis[(2-acetamido-3-hydroxy-3-oxo-propyl)sulfanyl]-4-chloro-2,6-dicyano-phenyl] sulfanylpropanoic acid (Ref: R613825) | - | Rat | - | ||||
,4-bis-amido-3,5,6-trichlorobenzenesulfonate (Ref: R471811) | - | Crop | - | ||||
2,4,5-trichloro-3-cyanobenzamide (Ref: R611966) | - | Rat | - | ||||
2,3,6-trichloro-5-cyanobenzamide (Ref: R611967) | - | Rat | - |
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Terrestrial ecotoxicology |
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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3 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat4 = Verified data |
High | |||||||
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10 | - | |||||||||
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100 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat Reproductive NOAEL5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Coturnix japonica5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 5200 mg kg feed⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Coturnix japonica5 = Verified data used for regulatory purposes |
- | ||||||||
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58.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus NOAEL5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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268.5 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida4 = Verified data |
Moderate | ||||||||
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50.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 4.8 mg kg⁻¹ soil |
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18 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Folsomia candida5 = Verified data used for regulatory purposes |
- | ||||||||
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> 4.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Avena sativa Allium cepa5 = Verified data used for regulatory purposes Vegetative vigour, ER₅₀ as kg product ha⁻¹, product chlorothalonil 75 WG |
- | ||||||||
> 8000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Maize Onion Oat Radish5 = Verified data used for regulatory purposes Seedling emergence, ER₅₀ as mL/product ha⁻¹, product chlorothalonil 500 SC |
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> 101 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
Low | |||||||
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> 63 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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53.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
- | ||||||||
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> 100 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Bombus terrestris5 = Verified data used for regulatory purposes |
Low | |||||||
- | |||||||||||
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> 94 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Bombus terrestris5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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8.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chrysoperla carnea5 = Verified data used for regulatory purposes |
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> 262 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi5 = Verified data used for regulatory purposes |
- | ||||||||
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> 2095 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri5 = Verified data used for regulatory purposes |
- | ||||||||
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0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Poecilus cupreus5 = Verified data used for regulatory purposes |
- |
Aquatic ecotoxicology |
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0.017 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
High | ||||||||
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0.0014 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Pimephales promelas5 = Verified data used for regulatory purposes |
High | ||||||||
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0.083 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio EC₅₀ Embryo3 = Unverified data of known source |
High | ||||||||
|
0.054 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.009 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
|
0.156 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Ceriodaphnia dubia LC₅₀4 = Verified data |
Moderate | ||||||||
|
- | - | - | ||||||||
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0.061 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
High | ||||||||
|
0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
Moderate | ||||||||
|
- | - | - | ||||||||
|
0.29 | C4 C = AGRITOX dataset. Dataset is no longer available. Lemna gibba4 = Verified data |
Moderate | ||||||||
|
0.013 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Navicula pelliculosa5 = Verified data used for regulatory purposes |
Moderate | ||||||||
|
0.033 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Selenastrum capricornutum5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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- | - | - |
|
- | - | - |
|
General |
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High (class III) | - | - | ||||||||
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
|
5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rabbit5 = Verified data used for regulatory purposes |
- | ||||||||
|
0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat 4 hr (nose only)5 = Verified data used for regulatory purposes |
- | ||||||||
|
- | - | - | ||||||||
|
0.015 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
|
0.05 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
|
0.01 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
|
0.003 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
|
0.02-1.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) concentration dependent5 = Verified data used for regulatory purposes |
- | ||||||||
|
- | - | - | ||||||||
|
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Low risk for prescribed pattern of use | |||||||||
|
PPE/PPC recommended/advised | ||||||||||
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UK MRL for Chlorothalonil is set to be reduced to the limit of quantification from September 2022 | ||||||||||
|
- | - | - | ||||||||
|
- | - | - | ||||||||
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Mammals eliminate almost all of the chemical in faeces (65-90%), urine and expired air | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- |
Health issues |
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May cause contact dermatitis IARC group 2B carcinogen; US EPA - probable human carcinogen, formation of tumours shown to form in mice following ingestion; CLP data - suspected carcinogen Endocrine issues - Activation of androgen-sensitive cells proliferation |
Handling issues |
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|
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Avoid generating spray mists/dust Not explosive or oxidising IMDG Transport Hazard Class 6.1 Not expected to auto-ignite; Not highly flammable |
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Health: H317, H318, H330, H335, H351 Environment: H400, H410 |
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U (Unlikely to present an acute hazard) | |||
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UN2811 | |||
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Packaging Group II (moderate danger) | |||
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- |
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chlorothalonil | ||
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chlorothalonil | ||
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Chlorthalonil | ||
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chlorothalonil | ||
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clorotalonil | ||
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clorotalonil | ||
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chlorothalonil | ||
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chlorotalonil | ||
|
- | ||
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chlotalonil | ||
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chloorthalonil | ||
|
- |
Record last updated: | 22/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |