Isodrin (Ref: ENT 19244) |
Last updated: 11/09/2023 |
(Also known as: Experimental insecticide 711 ; Compound 711; SD 3418; Isomer of aldrin) |
SUMMARY |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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Warning: Significant data are missing |
Warning: Significant data are missing |
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An obsolete persistent organochlorine insecticide that was mainly used to control malarial mosquitoes as an alternative to DDT | |
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Mosquitoes | |
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Humans | |
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Considered obsolete but may be available in some countries | |
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circa 1940s, introduced |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Chemical structure |
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Isomeric. The 5S,8R isomeris known as aldrin | |
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C₁₂H₈Cl₆ | |
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C1C2C=CC1C3C2C4(C(=C(C3(C4(Cl)Cl)Cl)Cl)Cl)Cl | |
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C1[C@@H]2C=C[C@H]1[C@@H]3[C@H]2[C@@]4(C(=C([C@]3(C4(Cl)Cl)Cl)Cl)Cl)Cl | |
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QBYJBZPUGVGKQQ-DIFDVCDBSA-N | |
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InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5-,6-,7+,10+,11+/m1/s1 | |
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Yes |
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Common Name | Relationship | Link |
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isodrin | - |
General status |
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Insecticide | |
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Cyclodiene insecticide; Organochlorine insecticide | |
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Synthetic | |
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Central nervous system stimulant. GABA-gated chloride channel antagonist. Also stomach and contact toxin | |
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465-73-6 | |
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207-366-2 | |
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None allocated | |
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102090390 | |
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No data found | |
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364.91 | |
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(1R,4S,4aS,5R,8S,8aR)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene | |
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(1R,4S,5R,8S)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene | |
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(1R,4S,4aS,5R,8S,8aR)-rel-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene | |
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WFD priority substance; Banned | |
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EU Directive 2008/105/EC EQS for the sum of all cyclodiene pesticides in: inland surface waters: 0.01 µg l⁻¹; Other surface waters; 0.005 µg l⁻¹ as annual average UK Statutory standard for the protection of aquatic life in inland, coastal and territorial waters: 0.03 µg l⁻¹ as annual average |
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Not applicable | |
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Not applicable | |
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2A | |
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Not applicable | |
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Leptocorisa acuta, Leptocorisa oratorius, Lucilia cuprina | |
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Crystalline solid | |
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Formulations |
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0.014 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) at 25 °C3 = Unverified data of known source |
Low | ||||||||
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240.6 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Decomposes before boiling | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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100 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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5.62 X 1006 | Calculated | - | |||||||
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6.75 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
High | ||||||||
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Likely to be soluble | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Based on chemical group | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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5.866 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) at 25 °C3 = Unverified data of known source |
Moderately volatile. If applied directly to plants or soil, drift is a concern & mitigation is advisable | ||||||||
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39.21 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) at 25 °C3 = Unverified data of known source |
Moderately volatile | ||||||||
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Degradation |
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Very persistent | ||||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | V1 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 1 = Estimated data with little or no verification |
Non-mobile | |||||||
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11000 | ||||||||||
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Estimated | ||||||||||
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Fate indices |
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Cannot be calculated | - | - | |||||||||||||||||||||||||
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Known soil metabolites |
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Known groundwater metabolites |
None
Other known metabolites |
None
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Terrestrial ecotoxicology |
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7.0 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
High | ||||||||
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Aquatic ecotoxicology |
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0.012 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Lepomis macrochirus4 = Verified data |
High | ||||||||
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1.0 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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7.0 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
High | ||||||||
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23.0 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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May be absorbed by inhalation, ingestion or skin absorption | ||||||||||
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Health issues |
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May cause respiratory depression and convulsions leading to coma Liver and CNS toxicant May cause headache, nausea, vomiting, dizziness, and tremors |
Handling issues |
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Unstable and may react with UV light, oxidising agents, phenols and acids May decompose at high temperatures to produce toxic gases |
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Health: H300, H310, H330 Environment: H400, H410 |
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Not classified: Obsolete (Not classified: Obsolete) | |||
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isodrin | ||
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isodrine | ||
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Record last updated: | 11/09/2023 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |