Clothianidin (Ref: CGA 322704) |
Last updated: 24/10/2024 |
(Also known as: Tl 435; HSDB 7281; thiamethoxam metabolite) |
SUMMARY |
Clothianidin is an insecticide for the control of sucking and chewing pests. It is moderately soluble and volatile but has a high potential for leaching to groundwater. It is very persistent in soil and water. Risk of bioaccumulation is low and its acute toxicity to mammals is considered moderate. It is, however, a neurotoxicant. It is toxic to some aquatic organisms but not greatly so to fish. It is highly toxic to honeybees but low risk to earthworms. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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An insecticide used to control sucking and chewing pests on a range of crops including rice, maize and fruit | |
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Corn rootworm, Southern corn billbug, Chinch flea beetle, Corn leaf aphid, Cutworms; Seedcorn maggots; Stinkbugs; Thrips; Wireworms; Flea beetles | |
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Corn; OSR; Rice; Orchards - apples, apricots, peach, pear, nectarines etc.; Potatoes; Ornamentals; Kohlrabi; Cabbage; Pistachio | |
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- | |
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Current | |
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2002, introduced |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Denmark/Spain | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Iran |
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Chemical structure |
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Isomeric - exists predominantly in the E-form. | |
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C₆H₈ClN₅O₂S | |
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CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-] | |
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- | |
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PGOOBECODWQEAB-UHFFFAOYSA-N | |
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InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)/f/h8,10H/b11-6+ | |
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Yes |
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Common Name | Relationship | Link |
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clothianidin | E-isomer |
General status |
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Insecticide, Metabolite, Other substance | |
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Soil | |
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Biocide, Wood preservative | |
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Neonicotinoid insecticide; Thiazole insecticide; Nitroguanidine insecticide | |
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960 g kg⁻¹ | |
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EU dossier - None declared | |
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Synthetic | |
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Translaminar and root systemic activity. Nicotinic acetylcholine receptor (nAChR) channel blocker. | |
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210880-92-5 | |
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433-460-1 | |
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738 | |
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044309 | |
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213027 | |
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613-307-00-5 | |
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249.7 | |
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(E)-N-[(2-chloro-1,3-thiazol-5-yl)methyl]-N'-methyl-N'-nitroguanidine | |
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(E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine | |
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(C(E))-N-((2-chloro-5-thiazolyl)methyl)-N'-methyl-N'-nitroguanidine | |
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Some applications are approved under GB Biocides Products Regulations; Ban or usage restriction may be in place for use on flowering crops in some Member States | |
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- | |
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Not applicable | |
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Not applicable | |
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4A | |
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Not applicable | |
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Leptinotarsa decemlineata, Myzus persicae | |
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White to beige-brownish powder or needles |
Can be a metabolite of: |
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thiamethoxam | Soil | 0.356 | Major fraction |
Formulations |
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Usually supplied as a flowable concentrate prepared for uses as a seed treatment |
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327 | E4 E = Manufacturers safety data sheets 4 = Verified data |
Moderate | ||||||||
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1.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Heptane5 = Verified data used for regulatory purposes |
- | ||||||||
12.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Xylene5 = Verified data used for regulatory purposes |
- | |||||||||
15200 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
- | |||||||||
2030 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | |||||||||
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176.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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432.5 | E4 E = Manufacturers safety data sheets 4 = Verified data |
- | ||||||||
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- | - | - | ||||||||
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- | - | - | ||||||||
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8.04 X 1000 | Calculated | - | |||||||
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0.905 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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- | - | - | |||||||
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- | - | - | ||||||||
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1.61 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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11.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
Strong base | |||||||||||
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3.8 X 10-08 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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2.9 X 10-11 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-volatile | ||||||||
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- | - | - | |||||||
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- | - | - | ||||||||
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Neutral solution: 214.5nm = 7770, 265.5nm = 17100, 290nm = 5350 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - |
Degradation |
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545 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Very persistent | |||||||
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545 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Very persistent | ||||||||
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121.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Persistent | ||||||||
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- | - | - | ||||||||
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387 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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EU dossier lab studies DT₅₀ range 143-1001 days, field studies DT₅₀ range 13.3-305.4 days, DT₉₀ range 188- >1000 days; Other studies: field DT₅₀ range 277-1386 days (USA and Canada) | ||||||||||
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- | ||||||||||
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16.6 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 4.4-35.9 days, 3 field crops, various matrices, n=3 | ||||||||||
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0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | |||||||
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- | ||||||||||
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Stable | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Stable | |||||||
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Stable pH 4 to pH 9 at 20 °C, hydrolysis occurs in alkali media at elevated temperatures e.g. DT₅₀ 14.4 days at pH 9, 50 °C | ||||||||||
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56.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | ||||||||
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40.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Stable | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately mobile | |||||||
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123 | ||||||||||
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- | ||||||||||
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1.48 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately mobile | |||||||
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160 | ||||||||||
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0.829 | ||||||||||
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EU dossier Kf range 0.52-4.4 mL g⁻¹, Kfoc range 84-345 mL g⁻¹, 1/n range 0.809-0.865, Soils=5 | ||||||||||
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No |
Fate indices |
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3.74 | Calculated | High leachability | ||||||||||||||||||||||||||
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9.02 X 10-01 | Calculated | - | |||||||||||||||||||||||||
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- | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Moderately mobile | Calculated | - | ||||||||||||||||||||||||||
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1.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method. Assumed 1.5E+06 OH/cm³, 12 hr5 = Verified data used for regulatory purposes |
Below the level of concern for long-range air transport | ||||||||||||||||||||||||||
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Low risk | P3 P = Other non-EU, UK or US Governments and Regulators Based on LogP < 33 = Unverified data of known source |
Low risk | |||||||||||||||||||||||||
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Known soil metabolites |
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Minor fraction | 0.091 | - | |||||
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Major fraction | 0.107 | - | |||||
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Minor fraction | 0.044 | - | |||||
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Minor fraction | - | - | |||||
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Minor fraction | 0.063 | - | |||||
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Minor fraction | - | - |
Known groundwater metabolites |
None
Other known metabolites |
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2-chlorothiazol-5-ylmethylguanidine | TZG; Thiazolguanidine | Rat | - | ||||
2-Chlorothiazol-5-ylmethylurea | TZU; Thiazolylurea | Rat | - | ||||
nitroguanidine Note: DT50 soil: 57-95 days; Koc 20.5 days |
NTG | Animal; Rat | - | ||||
urea | - | Rat | - | ||||
formamide | FA | Water | 0.160 | ||||
methylurea | MU | Water | 0.11 | ||||
methylguanidine Note: Tociologically relvant |
MG | a=Water (Photolysis); b=Plants; c=Rat | a=0.350 | ||||
5-aminomethyl-2-chlorothiazole | ACT | Rat | - | ||||
2-Chlorothiazole-5-carboxylic acid | CTCA | Rat | - | ||||
2-Methylthiothiazole-5-carboxylic acid | MTCA | Rat | - | ||||
N-2-chlorothiazol-5-ylmethyl-N-hydroxy-N’-methyl-N’’-nitroguanidine | THMN; thiazolhydroxymethylnitroguanidine | Rat | - | ||||
N-(2-chlorothiazol-5-ylmethyl)-N’-methylguanidine Note: Toxicologically relevant; Koc 525-3620 mL/g |
TMG; thiazolmethylguanidine | Plants; Sediment; Rat | - |
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Terrestrial ecotoxicology |
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> 500 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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10.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
High | |||||||
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- | - | |||||||||
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32.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Unknown species Reproductive NOAEL5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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430 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 752 mg kg bw⁻¹ day⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
- | ||||||||
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56.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus NOEC5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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13.21 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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2.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 0.75 kg ha⁻¹ |
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0.044 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | |||||||
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0.004 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | ||||||||
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0.02 | R4 R = Peer reviewed scientific publications Bombus terrestris4 = Verified data |
High | |||||||
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0.1 | R4 R = Peer reviewed scientific publications Osmia lignaria4 = Verified data |
High | |||||||
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> 8.4 | R4 R = Peer reviewed scientific publications Osmia bicornis4 = Verified data |
Moderate | ||||||||
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0.08 | R4 R = Peer reviewed scientific publications Megachile rotundata4 = Verified data |
High | |||||||
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Oral | ||||||||||
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0.014 | R4 R = Peer reviewed scientific publications Andrena prostomias4 = Verified data |
High | |||||||
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Oral 48 hr | ||||||||||
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> 10 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Coccinella septempunctata Larva4 = Verified data |
- | ||||||||
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97 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chrysoperla carnea Adult5 = Verified data used for regulatory purposes |
- | ||||||||
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1.086 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi Adult5 = Verified data used for regulatory purposes |
- | ||||||||
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126.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri Adult5 = Verified data used for regulatory purposes |
- | ||||||||
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23.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Poecilus cupreus Adult5 = Verified data used for regulatory purposes |
- |
Aquatic ecotoxicology |
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> 104.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Low | ||||||||
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20.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Pimephales promelas5 = Verified data used for regulatory purposes |
Low | ||||||||
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- | - | - | ||||||||
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> 40 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.12 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 100 | R4 R = Peer reviewed scientific publications Ceriodaphnia dubia4 = Verified data |
Low | ||||||||
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- | - | - | ||||||||
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0.029 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
High | ||||||||
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0.00072 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
High | ||||||||
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- | - | - | ||||||||
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> 121 | Q2 Q = Miscellaneous data from online sources Lemna gibba2 = Unverified data of unknown source |
Low | ||||||||
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55 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Pseudokirchneriella subcapitata5 = Verified data used for regulatory purposes |
Low | ||||||||
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- | - | - | ||||||||
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0.0031 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aquatic community5 = Verified data used for regulatory purposes |
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- | - | - |
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General |
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High (class III) | - | - | ||||||||
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> 500 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rabbit5 = Verified data used for regulatory purposes |
- | ||||||||
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> 5.54 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
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0.097 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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2.25 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Minimal risk from dietary exposure Risk assessment indicates ARfD would not normally be execeeded |
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Risk of exposure acceptable under label recommendations for use for personal protection clothing and equipment | ||||||||||
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GB MRL expected to deviate from the EU MRL in mid-2023 | ||||||||||
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Health issues |
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Effects consistent with endocrine disruption have been noted in rodents and dogs May cause hypotension, hypothermia and impaired pupillar function |
Handling issues |
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Not explosive Not expected to auto-ignite; Not highly flammable |
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Health: H302 Environment: H400, H410 |
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II (Moderately hazardous) | |||
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Limited shelf-life. Store at 0-6 DegC |
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clothianidin | ||
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clothianidine | ||
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Clothianidin | ||
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clothianidin | ||
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clotianidin | ||
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clotianidin | ||
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chlotianidyna | ||
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Record last updated: | 24/10/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |