The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate Moderate alert: Drainflow: Slightly mobile; Potential for particle bound transport: Medium
Ecotoxicity High alert: Fish acute ecotoxicity: High; Daphnia acute ecotoxicity: High; Earthworms acute ecotoxicity: High
Human health Moderate alert: Possible Carcinogen; Reproduction/development effects
GENERAL INFORMATION
Description
A 'green chemistry' fungicide derived from renewable raw materials which offers curative and protectant disease control of a wide range of pathogens in multiple crops
Example manufacturers & suppliers of products using this active now or historically
Dow AgroSciences LLC
Corteva Agriscience
Example products using this active
Adavelt
Zetigo
Formulation and application details
Usually supplied as an emulsifiable concentrate formulation
ENVIRONMENTAL FATE
Property
Value
Source; quality score; and other information
Interpretation
Solubility - In water at 20 °C (mg l⁻¹)
4.0
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Low
Solubility - In organic solvents at 20 °C (mg l⁻¹)
250000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Methanol
-
250000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Acetone
-
190
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
n-Heptane
-
250000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Ethyl acetate
-
Melting point (°C)
91
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
-
Boiling point (°C)
Decomposes before boiling
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
-
Degradation point (°C)
150
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
-
Flashpoint (°C)
-
-
-
Octanol-water partition coefficient at pH 7, 20 °C
P
1.58 X 1004
Calculated
-
Log P
4.2
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
High
Fat solubility of residues
Solubility
-
-
-
Data type
-
-
-
Density (g ml⁻¹)
1.28
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
-
Dissociation constant pKa) at 25 °C
-
-
-
-
Vapour pressure at 20 °C (mPa)
5.0 X 10-03
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Low volatility
Henry's law constant at 25 °C (Pa m³ mol⁻¹)
6.0 X 10-06
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Non-volatile
Volatilisation as max % of applied dose lost
From plant surface
-
-
-
From soil surface
-
-
-
Maximum UV-vis absorption L mol⁻¹ cm⁻¹
Max at 265nm & 271nm
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
-
Surface tension (mN m⁻¹)
-
-
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
General biodegradability
-
Soil degradation (days) (aerobic)
DT₅₀ (typical)
-
-
-
DT₅₀ (lab at 20 °C)
185
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Persistent
DT₅₀ (field)
2.5
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Non-persistent
DT₉₀ (lab at 20 °C)
-
-
-
DT₉₀ (field)
-
-
-
DT₅₀ modelling endpoint
-
-
-
Note
Australian Dossier 2022: Lab studies DT₅₀ (normalised) range 99-287 days, Field studies: DT₅₀ (measured) range 1.7-4.1 days
Dissipation rate RL₅₀ (days) on plant matrix
Value
-
-
-
Note
-
Dissipation rate RL₅₀ (days) on and in plant matrix
Value
-
-
-
Note
-
Aqueous photolysis DT₅₀ (days) at pH 7
Value
0.12
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Fast
Note
-
Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7
Value
17
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Non-persistent
Note
pH sensitive: 13 days at pH4; 0.33 days at pH9
Water-sediment DT₅₀ (days)
-
-
-
Water phase only DT₅₀ (days)
31
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Stable
Air degradation
As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below.
Decay in stored produce DT₅₀
-
Soil adsorption and mobility
Property
Value
Source; quality score; and other information
Interpretation
Linear
Kd (mL g⁻¹)
-
-
-
Koc (mL g⁻¹)
-
Notes and range
-
Freundlich
Kf (mL g⁻¹)
22
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Slightly mobile
Kfoc (mL g⁻¹)
1299
1/n
0.89
Notes and range
Australian dossier 2022: Kf range 13-43 mL g⁻¹, Kfoc range 1453-26372 mL g⁻¹
pH sensitivity
-
Fate indices
Property
Value
Source; quality score; and other information
Interpretation
GUS leaching potential index
0.35
Calculated
Low leachability
SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate
Value
9.70 X 10-04
Calculated
-
Note
-
Potential for particle bound transport index
Medium
Calculated
-
Potential for loss via drain flow
Slightly mobile
Calculated
-
Photochemical oxidative DT₅₀ (hrs) as indicator of long-range air transport risk
-
-
-
Bio-concentration factor
BCF (l kg⁻¹)
-
-
-
CT₅₀ (days)
-
-
Known soil metabolites
Metabolite
Major/Minor fraction
Estimated maximum occurrence fraction
Notes
Ref: X1285649
Major fraction
0.930
-
Ref: X12485631
Major fraction
0.330
-
Ref: X12485473
Major fraction
0.120
-
Known groundwater metabolites
None
Other known metabolites
None
ECOTOXICOLOGY
Terrestrial ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Mammals - Acute oral LD₅₀ (mg kg⁻¹)
> 2000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
rat
Low
Mammals - Short term dietary NOEL
(mg kg⁻¹)
-
-
-
(ppm diet)
-
-
Mammals - Chronic 21d NOAEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Birds - Acute LD₅₀ (mg kg⁻¹)
> 2000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Anas platyrhynchos
Low
Birds - Short term dietary (LC₅₀/LD₅₀)
-
-
-
Birds - Chronic 21d NOEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Earthworms - Acute 14 day LC₅₀ (mg kg⁻¹)
> 3.3
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Eisenia andrei corr
High
Earthworms - Chronic NOEC, reproduction (mg kg⁻¹)
-
-
-
Soil micro-organisms
-
-
-
Collembola
Acute LC₅₀ (mg kg⁻¹)
-
-
-
Chronic NOEC (mg kg⁻¹)
-
-
-
Non-target plants
> 134
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Solanum lycopersicum Vegetative vigour ER25 as g ha⁻¹
-
> 300
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
ten species tested Seedling emergence ER25 as g ha⁻¹
-
Honeybees (Apis spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 100
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera
Low
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 108
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera
Low
Unknown mode acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Chronic NOEDD µg bee⁻¹
13
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera Adults
-
Bumblebees (Bombus spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Mason bees (Osmia spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Other bee species (1)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Other bee species (2)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Beneficial insects (Ladybirds) Mortality LR₅₀ g ha⁻¹
161
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Coccinella septempunctata
-
Beneficial insects (Lacewings) Mortality LR₅₀ g ha⁻¹
467
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Chrysoperla carnea
-
Beneficial insects (Parasitic wasps) Mortality LR₅₀ g ha⁻¹
297
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Aphidius rhopalosiphi
-
Beneficial insects (Predatory mites) Mortality LR₅₀ g ha⁻¹
55.0
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Typhlodromus pyri
-
Beneficial insects (Ground beetles)
-
-
-
Aquatic ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Temperate Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)
> 0.011
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Oncorhynchus mykiss
High
Temperate Freshwater Fish - Chronic 21 day NOEC (mg l⁻¹)
-
-
-
Tropical Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242