Cyclobutrifluram is a multi-use pesticide which is mostly used as a nematicide. It is slightly soluble in water, very soluble in most organic solvents and is non-volatile. It can be persistent in soil systems under certain conditions - it degrades quicker in moist soils than in dry ones. It tends to demonstrate a low toxicity to humans or biodiversity.
Data alerts
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
Environmental fate High alert: Persistent; GUS: High leachability
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
-
Surface tension (mN m⁻¹)
-
-
-
Degradation
Property
Value
Source; quality score; and other information
Interpretation
General biodegradability
-
Soil degradation (days) (aerobic)
DT₅₀ (typical)
23
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Non-persistent
DT₅₀ (lab at 20 °C)
23
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data
Non-persistent
DT₅₀ (field)
138
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Persistent
DT₉₀ (lab at 20 °C)
-
-
-
DT₉₀ (field)
-
-
-
DT₅₀ modelling endpoint
-
-
-
Note
Australian dossier 2024: Lab study: DT₅₀ in moist soil = 14.7 days, in dry soil DT₅₀ 52.8 days. Field studies: DT₅₀ slow under dark aerobic conditions DT₅₀ range 27.1-248 days
Dissipation rate RL₅₀ (days) on plant matrix
Value
-
-
-
Note
-
Dissipation rate RL₅₀ (days) on and in plant matrix
Value
-
-
-
Note
-
Aqueous photolysis DT₅₀ (days) at pH 7
Value
18
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Slow
Note
DT₅₀ of 11 to 24 days under summer sunlight
Aqueous hydrolysis DT₅₀ (days) at 20 °C and pH 7
Value
Stable
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Stable
Note
Stable at pH4,7 & 9 at temps up to 70 °C
Water-sediment DT₅₀ (days)
697
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Stable
Water phase only DT₅₀ (days)
-
-
-
Air degradation
As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below.
Decay in stored produce DT₅₀
-
Soil adsorption and mobility
Property
Value
Source; quality score; and other information
Interpretation
Linear
Kd (mL g⁻¹)
-
-
-
Koc (mL g⁻¹)
-
Notes and range
-
Freundlich
Kf (mL g⁻¹)
6.46
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Moderately mobile
Kfoc (mL g⁻¹)
333
1/n
0.87
Notes and range
Australian dossier: Kf range 3.39-9.53 L/kg, Koc range 210-585 L/kg
pH sensitivity
Weak correlation with OC
Fate indices
Property
Value
Source; quality score; and other information
Interpretation
GUS leaching potential index
3.16
Calculated
High leachability
SCI-GROW groundwater index (μg l⁻¹) for a 1 kg ha⁻¹ or 1 l ha⁻¹ application rate
Value
4.12 X 10-01
Calculated
-
Note
-
Potential for particle bound transport index
Medium
Calculated
-
Potential for loss via drain flow
Moderately mobile
Calculated
-
Photochemical oxidative DT₅₀ (hrs) as indicator of long-range air transport risk
1.73
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Calculated using the Atkinson method, 12 hr
Below the level of concern for long-range air transport
Bio-concentration factor
BCF (l kg⁻¹)
-
-
-
CT₅₀ (days)
-
-
Known soil metabolites
Metabolite
Major/Minor fraction
Estimated maximum occurrence fraction
Notes
Ref: CGA177291
Major fraction
0.140
P5
Ref: EXC8199
Major fraction
0.115
P5
Known groundwater metabolites
None
Other known metabolites
Metabolite name and reference
Aliases
Formation medium / Rate
Estimated maximum occurrence fraction
Ref: SYN510275
-
Rat; Animal; Plant
-
Ref: SYN549104
-
Plant; Animal
-
Ref: SYN552301
-
Plant
-
Ref: SYN552202
-
Plant
-
Ref: SYN510275
-
Plant
-
Ref: SYN510260
-
Plant
-
trifluoroacetic acid
-
Plant
-
ECOTOXICOLOGY
Terrestrial ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Mammals - Acute oral LD₅₀ (mg kg⁻¹)
> 5000
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Rat
Low
Mammals - Short term dietary NOEL
(mg kg⁻¹)
-
-
-
(ppm diet)
-
-
Mammals - Chronic 21d NOAEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Birds - Acute LD₅₀ (mg kg⁻¹)
> 1264
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Colinus virginianus
Moderate
Birds - Short term dietary (LC₅₀/LD₅₀)
-
-
-
Birds - Chronic 21d NOEL (mg kg⁻¹ bw d⁻¹)
-
-
-
Earthworms - Acute 14 day LC₅₀ (mg kg⁻¹)
> 500
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Eisenia andrei
Moderate
Earthworms - Chronic NOEC, reproduction (mg kg⁻¹)
212
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Eisenia andrei
Low
Soil micro-organisms
-
-
-
Collembola
Acute LC₅₀ (mg kg⁻¹)
-
-
-
Chronic NOEC (mg kg⁻¹)
-
-
-
Non-target plants
> 900
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Various plants n=10 Seedling emergence, ER₅₀ as g ha⁻¹
-
> 900
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Various plants n=10 Vegetative vigour, ER₅₀ as g ha⁻¹
-
Honeybees (Apis spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 200
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera
Low
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 72
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera
Moderate
Unknown mode acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
> 30
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Apis mellifera Larvae
Moderate
Chronic
-
-
-
Bumblebees (Bombus spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
-
Mason bees (Osmia spp.)
Contact acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Oral acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg bee⁻¹)
-
-
-
Other bee species (1)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Other bee species (2)
Acute LD₅₀ (worst case from 24, 48 and 72 hour values - μg insect⁻¹)
-
-
-
Mode of exposure
-
Beneficial insects (Ladybirds)
-
-
-
Beneficial insects (Lacewings)
-
-
-
Beneficial insects (Parasitic wasps)
-
-
-
Beneficial insects (Predatory mites)
-
-
-
Beneficial insects (Ground beetles)
-
-
-
Aquatic ecotoxicology
Property
Value
Source; quality score; and other information
Interpretation
Temperate Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)
11.0
P5 P = Other non-EU, UK or US Governments and Regulators 5 = Verified data used for regulatory purposes
Pimephales promelas
Moderate
Temperate Freshwater Fish - Chronic 21 day NOEC (mg l⁻¹)
-
-
-
Tropical Freshwater Fish - Acute 96 hour LC₅₀ (mg l⁻¹)
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242