Pyrifenox (Ref: CGA 179945) |

Last updated: 03/09/2023
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(Also known as: ethanone; NRK 297) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A fungicide for the control of powdery mildew, scab and other fungal pathogens on a range of crops |
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Powdery mildew; Scab; Leafspot; Blossom blight |
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Fruit including apples, pears, cherries, peaches, apricots; Peanuts; Sugarbeet; Vegetables |
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- |
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- |
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1986, first reported and marketed |
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Not approved |
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Expired |
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No UK approval for use as a pesticide |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Expired |
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- |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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Isomeric existing in the Z- and E-forms |
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C₁₄H₁₂Cl₂N₂O |
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CON=C(CC1=CN=CC=C1)C2=C(C=C(C=C2)Cl)Cl |
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CO/N=C(/CC1=CN=CC=C1)\C2=C(C=C(C=C2)Cl)Cl |
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CKPCAYZTYMHQEX-UHFFFAOYSA-N |
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InChI=1S/C14H12Cl2N2O/c1-19-18-14(7-10-3-2-6-17-9-10)12-5-4-11(15)8-13(12)16/h2-6,8-9H,7H2,1H3/b18-14- |
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Yes |
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Fungicide |
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Pyridine fungicide |
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- |
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- |
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Synthetic |
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Systemic with protective and curative action. Disrupts membrane function. |
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88283-41-4 |
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618-138-0 |
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448 |
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- |
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6023583 |
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No data found |
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295.16 |
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- |
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2',4'-dichloro-2-(3-pyridyl)acetophenone (EZ)-O-methyloxime |
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1-(2,4-dichlorophenyl)-2-(3-pyridinyl)ethanone O-methyloxime |
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PAN listed Highly Hazardous Chemical |
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- |
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Not applicable |
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Not applicable |
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Not applicable |
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3 |
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- |
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Pale yellow viscous liquid |
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Usually supplied as an emulsifiable concentrate or wettable powder. |
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300 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderate |
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210000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source n-Hexane |
- |
Miscible |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Acetone |
- |
Miscible |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Toluene |
- |
Miscible |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Ethanol |
- |
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Not applicable |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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212 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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- |
- |
- |
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106 |
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source |
- |
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2.51 X 1003 |
Calculated |
- |
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3.4 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
High |
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- |
- |
- |
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- |
- |
- |
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1.28 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
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4.61 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
- |
Weak acid |
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1.7 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Low volatility. If applied directly to plants or soil, drift is a concern & mitigation is advisable |
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5.80 X 10-03 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
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66 |
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Moderately persistent |
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- |
- |
- |
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66 |
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Moderately persistent |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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Defra DT₅₀ range 50-120 days |
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- |
- |
- |
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- |
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- |
- |
- |
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- |
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0.73 |
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Fast |
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- |
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56 |
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Moderately persistent |
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Other data: Stable pH 3 to pH 9 (L3) |
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- |
- |
- |
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365 |
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Stable |
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- |
- |
- |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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- |
Soil adsorption and mobility |
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- |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Slightly mobile |
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980 |
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- |
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- |
- |
- |
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- |
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- |
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- |
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- |
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1.84 |
Calculated |
Transition state |
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6.39 X 10-02 |
Calculated |
- |
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- |
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Medium |
Calculated |
- |
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Slightly mobile |
Calculated |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
None
Terrestrial ecotoxicology |
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2912 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
Low |
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15 |
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source Rat 2 yr |
High |
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- |
- |
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- |
- |
- |
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> 2000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Anas platyrhynchos |
Low |
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- |
- |
- |
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- |
- |
- |
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733 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
- |
- |
- |
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70 |
Apis mellifera |
Moderate |
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59 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Apis mellifera |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
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- |
- |
- |
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- |
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- |
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- |
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- |
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> 6.6 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Lepomis macrochirus |
Moderate |
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- |
- |
- |
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- |
- |
- |
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> 3.6 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Daphnia magna |
Moderate |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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0.095 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Scenedesmus subspicatus |
Moderate |
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- |
- |
- |
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- |
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- |
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- |
- |
- |
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- |
- |
- |
HUMAN HEALTH AND PROTECTION |
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High (class III) |
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- |
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2912 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
Low |
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5000 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
- |
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2.05 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Rat |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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- |
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- |
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EU MRL pesticide database |
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- |
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- |
- |
- |
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- |
- |
- |
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- |
- |
- |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A3 A = Chromosome aberration (EFSA database) 3 = Negative ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
✓Yes, known to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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XNo, known not to cause a problem |
No data found |
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Harmful if swallowed Endocrine issues - Weak estrogen inhibition |
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No information available |
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Health: H302 Environment: H400, H410 |
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III (Slightly hazardous) |
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- |
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- |
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- |
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pyrifenox |
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pyrifénox |
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Pyrifenox |
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pyrifenox |
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pirifenox |
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pirifenox |
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- |
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pyrifenoks |
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- |
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- |
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pyrifenox |
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- |
Record last updated: |
03/09/2023 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |