Buprofezin (Ref: PP 618) |
Last updated: 31/10/2024 |
(Also known as: buprofezine; NNI 750; ST-29285) |
SUMMARY |
Buprofezin is a thiadiazine insecticide for whitefly and other insect control. It has a low aqueous solubility and a low volatility. Depending on local conditions it can be moderately persistent in soils and very persistent in water systems. It is not expected to leach to groundwaters. It is moderately toxic to most fauna and flora, the main exception being honeybees for which buprofezin has a low toxicity. It also has a low oral toxicity for mammals. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A moulting inhibitor, thiadiazine insecticide for whitefly and other insect control | |
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Whitefiles, Leaf- and plant-hoppers, Scale insects, Lady beetles, Mealybugs | |
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Citrus crops; Top fruit; Cucumbers; Tomatoes; Sweet potatoes; Rice; Cotton; Ornamentals | |
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Efficacy established via extensive European field trials | |
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Current | |
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1981, first reported; 1984 first introduced |
UK regulatory status |
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Approved | ||
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31/01/2031 | ||
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None |
EC Regulation 1107/2009 (repealing 91/414) |
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Approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Italy/Austria | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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15/12/2025 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Australia, USA, Morocco |
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Chemical structure |
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Theoretically can exists in both the Z- and E- form, but X-ray analysis indicates that buprofezin consists of the Z-isomer exclusively (both in solid and in dissolved state). | |
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C₁₆H₂₃N₃OS | |
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CC(C)N1C(=NC(C)(C)C)SCN(C1=O)C2=CC=CC=C2 | |
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- | |
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PRLVTUNWOQKEAI-VKAVYKQESA-N | |
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InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3/b17-14- | |
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Yes |
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Common Name | Relationship | Link |
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buprofezin | - |
General status |
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Insecticide, Acaricide, Insect Growth Regulator | |
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Unclassified IGR | |
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985 g kg⁻¹ | |
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EU dossier - None declared | |
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Synthetic | |
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Contact and stomach action. Inhibitor of chitin biosynthesis. | |
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953030-84-7 | |
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69327-76-0 | |
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858-581-9 | |
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681 | |
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275100 | |
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50367 | |
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No data found | |
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305.44 | |
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(2Z)-2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one | |
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(Z)-2-tert-butylimino-3-isopropyl-5-phenyl-1,3,5-thiadiazinan-4-one | |
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2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methylethyl)-5-phenyl-4H-1,3,5-thiadiazin-4-one | |
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- | |
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- | |
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Not applicable | |
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Not applicable | |
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16 | |
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Not applicable | |
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Bemisia tabaci, Trialeurodes vaporariorum, Nilaparvata lugens | |
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White crystalline powder |
Formulations |
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Usually supplied as a soluble concentrate that is mixed with water and applied as a spray |
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0.637 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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520000 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Chloroform4 = Verified data |
- | ||||||||
336000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Toluene5 = Verified data used for regulatory purposes |
- | |||||||||
253000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
- | |||||||||
241000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | |||||||||
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104.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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252.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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- | - | - | ||||||||
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3.16 X 1004 | Calculated | - | |||||||
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4.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 25 °C5 = Verified data used for regulatory purposes |
High | ||||||||
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | |||||||
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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1.18 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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Not applicable | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
No dissociation | |||||||||||
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0.042 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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20.1 X 10-03 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-volatile | ||||||||
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22 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 24 hr5 = Verified data used for regulatory purposes |
Volatilisation is potentially a concern for short and long range air transport | |||||||
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9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 24 hr5 = Verified data used for regulatory purposes |
Volatilisation is not considered critical for air pollution | ||||||||
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Neutral solution: 245nm = 11515 Acidic solution: 229nm = 16463 Basic solution: 220nm = 9240, 245nm = 11650 |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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70.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 20°C5 = Verified data used for regulatory purposes |
- |
Degradation |
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- | ||||||||||
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55.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately persistent | |||||||
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55.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately persistent | ||||||||
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29.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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185.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Persistent | ||||||||
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191.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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EU 2021 dossier lab studies DT₅₀ (normalised) range 24.7-99.0 days, DT₉₀ (measured) range 82.7-329 days, Soils=4. Field studies DT₅₀ (normalised) range 11.2-86.6 days, DT₉₀ (measured) range 44.8-330 days, Soils-7; Other studies: Lab DT₅₀ range 26-274 days, field DT₅₀range 48-63 days | ||||||||||
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7.15 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
- | |||||||
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Mango, n=1 | ||||||||||
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7.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
- | |||||||
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Published literature RL₅₀ range 3.5-16.3 days, 7 field and undercover grown crops, various matrices, n=11; Peppers in cold storage RL₅₀=253 days | ||||||||||
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33 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Stable | |||||||
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- | ||||||||||
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Stable | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Stable | |||||||
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DT₅₀: 51 days at pH 5, 378 days at pH 7, 396 at pH 9 | ||||||||||
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49 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | ||||||||
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16.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slow | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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[Sweet peppers: No residue decay after 30 days in cold, dark conditions; Field study] |
Soil adsorption and mobility |
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103 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-mobile | |||||||
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5363 | ||||||||||
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EU dossier Kd range 4.27-318.12 mL g⁻¹, Koc range 854-21208 mL g⁻¹, Soils=7 | ||||||||||
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358.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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1502 | ||||||||||
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0.902 | ||||||||||
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EU 2021 dossier Kf range1.82-1980 mL g⁻¹, Kfoc range394.9-128331 mL g⁻¹, 1/n range 0.744-1.275, Soils=7; Other study Kf = 750 mean of 7 values. Clay OC=3.8% Kf=39.94; Sandy loam OC=2.7% Kf=303.9; Sand OC=0.5% Kf=1.98 | ||||||||||
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No |
Fate indices |
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1.21 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2.53 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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- | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - | ||||||||||||||||||||||||||
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2.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method. Assumed 1.5E+06 OH/cm³, 12 hr5 = Verified data used for regulatory purposes |
Below the level of concern for long-range air transport | ||||||||||||||||||||||||||
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509 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Whole fish5 = Verified data used for regulatory purposes |
Threshold for concern | |||||||||||||||||||||||||
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0.5 | - |
Known soil metabolites |
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Minor fraction | 0.01 | - | |||||
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Minor fraction | 0.04 | - | |||||
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Minor fraction | 0.02 | - | |||||
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Minor fraction | 0.04 | - | |||||
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Minor fraction | 0.01 | - | |||||
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Minor fraction | 0.01 | - |
Known groundwater metabolites |
None
Other known metabolites |
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3-isopropyl-5-phenylperhydro-1,3,5-thiadiazin--2,4-dione Note: Mol wt = 250.3; Rat LD50(oral) = 300-2000 |
BF9 | Rat; Sediment | - | ||||
1-tert-butyl-3-isopropyl-5-phenylbiuret Note: Rat LD50(oral) >2000 |
BF11 | Rat; Surface water; Sediment | - | ||||
N-isopropyl-N-phenylurea Note: Mol wt = 178.1; Rat LD50(oral) = 300-2000 |
BF12 | Rat; Surface water; Sediment | - | ||||
1-tert-butyl-3-isopropy-5-phenyl-2-biuret Note: Rat LD50(oral) = 300-2000 |
BF25 | Plant | - | ||||
2-amino-2-methylpropyl-2-isopropyl-4-phenylallophanate Note: Mol wt = 293.4; Rat LD50(oral) = 50-300 |
BF26 | Plant | - | ||||
(2Z)-2-(tert-butylimino-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one-1-oxide | buprofezin sulphoxide; BF10 | Surface water; Sediment; Rat | - | ||||
2-(2-hydroxy-1,1-dimethylethyl)imino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-1H-1,3,5-thiadiazin-4-one Note: Rat LD50(oral) range 300-2000 |
BF4 | Rat | - | ||||
(2Z)-2-(tert-butylimino)-5-(4-hydroxyphenyl)-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one Note: CAS no. 69329-95-9 |
BF2 | Rat; Surface water (photolysis) | - | ||||
1-(4-hydroxyphenyl)-3-isopropyl urea | BF-13 | Rat (urine) | - | ||||
4-methyl-1-phenyl-1H-imidazole | buprofezin U-2 | Aqueous photolysis | - |
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Terrestrial ecotoxicology |
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> 1635 | B5 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 3.6 | B5 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat5 = Verified data used for regulatory purposes |
High | |||||||
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> 40 | - | |||||||||
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- | - | - | ||||||||
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> 2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 1306 mg kg bw⁻¹ day⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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> 500 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida corr5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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125 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida corr5 = Verified data used for regulatory purposes |
Low | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 5 kg ha⁻¹ |
- | ||||||||
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31.25 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Folsomia candida corr5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
- | - | - | |||||||||
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> 200 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
Low | |||||||
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> 163.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
Low | ||||||||
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- | - | - | |||||||
- | |||||||||||
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> 69 | R3 R = Peer reviewed scientific publications Bombus terrestris 77 day LC₅₀3 = Unverified data of known source |
Moderate | ||||||||
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> 3.96 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Chrysoperla carnea Larva4 = Verified data |
- | ||||||||
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> 3130 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi5 = Verified data used for regulatory purposes |
- | ||||||||
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> 3000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - |
Aquatic ecotoxicology |
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> 0.33 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.138 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 0.93 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio3 = Unverified data of known source |
Moderate | ||||||||
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> 0.42 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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- | - | - | ||||||||
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> 0.30 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Unknown species4 = Verified data |
Moderate | ||||||||
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- | - | - | ||||||||
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0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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5.54 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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2.33 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Lemna gibba4 = Verified data |
Moderate | ||||||||
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> 0.40 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Pseudokirchneriella subcapitata5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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- | - | - |
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- | - | - |
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General |
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High (class III) | - | - | ||||||||
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> 1635 | B5 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
- | ||||||||
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> 4.57 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat 4 hr5 = Verified data used for regulatory purposes |
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- | - | - | ||||||||
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0.01 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
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0.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
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- | - | - | ||||||||
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0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Dog SF=1005 = Verified data used for regulatory purposes |
- | ||||||||
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40 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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- | - | - | ||||||||
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Acceptable risk for proposed uses | |||||||||
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Acceptable risk for proposed uses | ||||||||||
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- | ||||||||||
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- | - | - | ||||||||
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Extensively metabolised and eliminated mainly in the faeces (60-76%) and urine (13-25%) | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Health issues |
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Possible liver and thyroid toxicant US EPA - some evidence of carcinogenicity but weak; CPL data - Suspected of causing cancer |
Handling issues |
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Not explosive or oxidising Not expected to auto-ignite; Not highly flammable |
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Health: H302, H373, H362, H351, H361d Environment: H400, H410 |
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III (Slightly hazardous) | |||
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buprofezin | ||
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buprofezine | ||
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Buprofezin | ||
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buprofezin | ||
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buprofezin | ||
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buprofezin | ||
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- | ||
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buprofezyna | ||
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buprofezin | ||
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buprofezin | ||
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buprofezin | ||
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- |
Record last updated: | 31/10/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |