Diazinon (Ref: OMS 469) |
Last updated: 01/11/2024 |
(Also known as: dimpylate; ENT 19507) |
SUMMARY |
Diazinon is a general purpose insecticide. It is moderately soluble and highly volatile. Based on its chemical properties it has a low risk of leaching to groundwater however, incidents of contamination have been noted and it should be considered a potential groundwater pollutant. It is non-persistent in soil but stable in aqueous environments. It is listed as a severe marine pollutant. Moderately toxic to mammals and earthworms. In humans and other mammals it is a neurotoxicant. Considered highly toxic to most aquatic organisms, honeybees and birds. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A broad spectrum insecticide used to control sucking and chewing insects on a wide range of crops including top fruit. Also has livestock applications. | |
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Bean fly; Thrips; Caterpillars; Cabbage white butterfly; Loopers; Cutworms; Livestock pests including mites, ticks, lice and biting flies | |
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Fruit including apples, pears, plums; Rice; Sugarcane; Horticultural crops; Vegetables including beans, brassicas, curcubits; onions | |
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- | |
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Current | |
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1953, first reported |
UK regulatory status |
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Not approved | ||
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Expired | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Portugal | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Expired | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Australia (phasing out), USA |
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Chemical structure |
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None | |
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C₁₂H₂₁N₂O₃PS | |
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CCOP(=S)(OCC)OC1=NC(=NC(=C1)C)C(C)C | |
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S=P(OCC)(OCC)Oc1nc(nc(c1)C)C(C)C | |
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FHIVAFMUCKRCQO-UHFFFAOYSA-N | |
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InChI=1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3 | |
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Yes |
General status |
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Insecticide, Acaricide, Semiochemical, Veterinary substance | |
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Organophosphate insecticide; Organophosphate acaricide; Organothiophosphate insecticide; Organothiophosphate acaricide; Oganophosphate repellent | |
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950 g kg⁻¹ (without stabilizer) | |
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EU dossier - O,S-TEPP, S,S-TEPP, TEPP24 and diazoxon | |
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Synthetic | |
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Non-systemic with respiratory, contact and stomach action. Acetylcholinesterase (AChE) inhibitor. | |
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333-41-5 | |
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206-373-8 | |
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15 | |
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057801 | |
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3017 | |
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015-040-00-4 | |
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304.35 | |
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O,O-diethyl O-[6-methyl-2-(propan-2-yl)pyrimidin-4-yl] phosphorothioate | |
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O,O-diethyl O-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate | |
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O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosphorothioate | |
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Potential groundwater contaminant; Severe Marine Pollutant; Chemical subject to PIC regulations | |
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UK statutory standard for surface water quality: ‘Good’ for freshwater, transitional and coastal waters 0.01 µg l⁻¹, 0.02 µg l⁻¹ 95th percentile | |
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Not applicable | |
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Not applicable | |
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1B | |
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Not applicable | |
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Aphis gossypii, Aphis pomi, Delia brassicae, Dialeurodes citri, Psilia rosae, many others | |
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Colourless to dark brown liquid |
Formulations |
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Available in a wide variety of formulations including concentrates for dilution and use as a crop spray, powders and impregnated collars for domestic pet use, shampoos, pour-ons and dips |
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60 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | ||||||||
9000000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
- | |||||||||
9000000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Methanol5 = Verified data used for regulatory purposes |
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9000000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Toluene5 = Verified data used for regulatory purposes |
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Not applicable | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Decomposes before boiling | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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140 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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4.90 X 1003 | Calculated | - | |||||||
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3.69 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | |||||||
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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1.11 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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2.6 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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Strong acid | |||||||||||
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11.97 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Highly volatile. If applied directly to plants or soil, drift is a concern & mitigation is advisable | ||||||||
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6.09 X 10-02 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile | ||||||||
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49.6 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 24 hr5 = Verified data used for regulatory purposes |
Volatilisation is potentially a concern for short and long range air transport | |||||||
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10.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 24 hr5 = Verified data used for regulatory purposes |
Volatilisation is not considered critical for air pollution | ||||||||
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Maxima at 246nm = 4050, 290nm = 20.86 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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49.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) at 20°C5 = Verified data used for regulatory purposes |
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Degradation |
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9.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | |||||||
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9.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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18.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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209 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Persistent | ||||||||
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61 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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EU dossier range lab studies DT₅₀ range 8-23 days, DT₉₀ range 46-372 days; field studies Germany DT₅₀ 7.5-29.3 days, DT₉₀ range 24.9-97 days; Other sources: DT₅₀ 40 days (DW4) | ||||||||||
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2.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 0.8-5.2 days, 5 field & undercover grown crops, various matrices, n=6 | ||||||||||
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3.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 1.0-9.6 days, 14 field & undercover grown crops, various matrices, n=14 | ||||||||||
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50 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Stable | |||||||
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- | ||||||||||
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138 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Persistent | |||||||
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pH variable: DT₅₀ 12 days at pH 5, 77 days at pH 9 | ||||||||||
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10.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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4.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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[Grapes: 4.9 days @ 25 DegC; 9.8 days @ 4 DegC; Field study], [Mushroom (Agaricus bisporus): 4.4 days @ 25 DegC; 4.47 days @ 4 DegC; 20.4 days @ -18 DegC; Lab study] |
Soil adsorption and mobility |
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27.1 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 3 = Unverified data of known source |
Slightly mobile | |||||||
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609 | ||||||||||
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EU dossier Kd range 3.7-113.5 mL g⁻¹, Koc range 430-841 mL g⁻¹, Soils=2; Other literature studies: Kd range 0.84-19.72 mL g⁻¹; Koc range 254-3779 mL g⁻¹, Soils=25 | ||||||||||
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4.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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643 | ||||||||||
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0.860 | ||||||||||
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EU dossier Kf range1.4-7.6 mL g⁻¹, Kfoc range 413-760 mL g⁻¹, 1/n range 0.820-0.901, Soils=4; Other literature studies: Kf range 0.70-25.73 mL g⁻¹, Kfoc range 259-4175 mL g⁻¹, 1/n range 0.79-1.25, Soils = 25 | ||||||||||
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Fate indices |
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1.51 | Calculated | Low leachability | ||||||||||||||||||||||||||
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3.36 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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Low | Calculated | - | ||||||||||||||||||||||||||
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Slightly mobile | Calculated | - | ||||||||||||||||||||||||||
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1.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method. Assumed 1.5E+06 OH/cm³5 = Verified data used for regulatory purposes |
Below the level of concern for long-range air transport | ||||||||||||||||||||||||||
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500 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) (Other literature log BCF range 0.7-3.5 (R3))5 = Verified data used for regulatory purposes |
Threshold for concern | |||||||||||||||||||||||||
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2 | - |
Known soil metabolites |
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Major fraction | 0.818 | - | |||||
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Minor fraction | - | - |
Known groundwater metabolites |
None
Other known metabolites |
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2-(1-hydroxymethyl)-ethyl-4-methyl-6-hydroxypyrimidine (Ref: CL-XIX-29) | - | Animal | - | ||||
2-isopropyl-4-hydroxymethyl-6-hydroxypyrimidine (Ref: JAK-III-57) | - | Animal | - | ||||
hydroxydiazinon (Ref: CGA 14128) | - | Animal; Plant | - | ||||
tetraethyl pyrophosphate (Ref: ENT 18771 ) | TEPP | Not applicable | - | ||||
O,O,O,O-tetraethyl-thiopyrophosphate | O,S-TEPP | Not applicable | - | ||||
O,O,O,O-tetraethyl-dithiopyrophosphate | S,S-TEPP | Not applicable | - | ||||
2-(1-hydroxy-1-methyl)-ethyl-4-methyl-6-hydroxpyrimidine (Ref: GS 31144) | - | Rat (Urine); Animal | - | ||||
O,O-diethyl O-(2-isopropyl-4-methylpyrimid-6-yl)phosphate Note: CAS = 962-58-3; Toxic |
diazoxon | Animal | - | ||||
diazinon hydroxylate | - | Animal | - |
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Terrestrial ecotoxicology |
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1139 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
High | |||||||
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35 | - | |||||||||
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1.44 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
High | ||||||||
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8 mg kg bw⁻¹ day⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Anas platyrhynchos5 = Verified data used for regulatory purposes |
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65 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 80 mg kg⁻¹ soil 28 Day |
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0.13 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | |||||||
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0.09 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | ||||||||
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0.007 | R4 R = Peer reviewed scientific publications Megachile rotundata4 = Verified data |
High | |||||||
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Contact | ||||||||||
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0.12 | R4 R = Peer reviewed scientific publications Nannotrigona perilampoides4 = Verified data |
High | |||||||
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Contact | ||||||||||
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0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chrysoperla carnea5 = Verified data used for regulatory purposes |
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811 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi5 = Verified data used for regulatory purposes |
- | ||||||||
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0.153 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri5 = Verified data used for regulatory purposes |
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Aquatic ecotoxicology |
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3.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 2.08 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio3 = Unverified data of known source |
Moderate | ||||||||
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0.001 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.00056 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.0002 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Ceriodaphnia dubia LC₅₀4 = Verified data |
High | ||||||||
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0.0042 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia3 = Unverified data of known source |
High | ||||||||
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0.023 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Chironomus riparius4 = Verified data |
High | ||||||||
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15.9 | R3 R = Peer reviewed scientific publications Chironomus dilutus Growth3 = Unverified data of known source |
Moderate | ||||||||
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6.4 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Unknown species4 = Verified data |
Moderate | ||||||||
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> 10 | Q1 Q = Miscellaneous data from online sources Unknown species1 = Estimated data with little or no verification |
Low | ||||||||
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0.0024 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Fish5 = Verified data used for regulatory purposes |
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General |
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High (class III) | - | - | ||||||||
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1139 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
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> 5.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
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Intraperitoneal LD₅₀ = 65.0 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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Intratracheal LD₅₀ = 210 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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0.0002 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Dog SF=1005 = Verified data used for regulatory purposes |
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0.025 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=1005 = Verified data used for regulatory purposes |
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0.0002 | A2 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Dog SF=1002 = Unverified data of unknown source |
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1.7-40.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) concentration dependent5 = Verified data used for regulatory purposes |
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List I; List II | - | - | ||||||||
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Possible risk to bystanders by inhalation | |||||||||
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Risk of exposure by dermal and inhalation routes Personal protection clothing and equipment must be worn |
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Quickly degrades, two main pyrimidinol metabolites are formed which are largely eliminated via urine, Rate varies with species. | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Health issues |
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IARC Group 2A carcinogen; US EPA - not likely to be a human carcinogen Endocrine issues - Estrogenic effect |
Handling issues |
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Not explosive IMDG Transport Hazard Class 6.1 Not expected to auto-ignite; Not highly flammable |
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Health: H302 Environment: H400, H410 |
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II (Moderately hazardous) | |||
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UN2811 | |||
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Packaging Group II (moderate danger) | |||
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diazinon | ||
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diazinon | ||
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Diazinon | ||
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diazinon | ||
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diazinone | ||
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diazinon | ||
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diazinon | ||
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diazynon | ||
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diazinon | ||
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diazinon | ||
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diazinon | ||
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Record last updated: | 01/11/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |