Famoxadone (Ref: JE 874) |
Last updated: 31/10/2024 |
(Also known as: DPX JE874; IN JE874) |
SUMMARY |
Famoxadone is an oxazolidinedione fungicide. It has a low aqueous solubility, low risk of leaching to groundwater and is volatile. It is not persistent in soil or water. Whilst it has a low mammalian toxicity there is a slight concern regarding its ability to bioaccumulate. It is considered to be a neurotoxicant and is a known eye and skin irritant. It is highly toxic to fish and aquatic invertebrates and moderately toxic to other aquatic organisms, earthworms and honeybees. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A fungicide used to control a broad spectrum of plant pathogenic fungi including downy mildew and blights | |
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Alternaria Leaf Blight, Anthracnose, Downy Mildew, Phytophthora blight | |
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Potatoes; Tomatoes; Salad crops; Peppers; Cucurbits; Grapes; Spinach; Rocket | |
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- | |
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Current | |
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1996 first reported; 1998, first introduced |
UK regulatory status |
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Not approved | ||
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Withdrawn | ||
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Check label - may vary with formulation |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Finland | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes - two 'Persistent-Bioaccumulative-Toxic' criteria | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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USA, Central and South America, South-east Asia, Africa, China, Japan |
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Chemical structure |
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A chiral molecule existing in the R- and S-forms. Substance is racemic (S-isomer to R-isomer ratio is about 1:1) | |
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C₂₂H₁₈N₂O₄ | |
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CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 | |
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- | |
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PCCSBWNGDMYFCW-UHFFFAOYSA-N | |
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InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3 | |
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Yes |
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Common Name | Relationship | Link |
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S-famoxadone | S-isomer |
General status |
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Fungicide | |
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Oxazole fungicide; Dicarboximide fungicide | |
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960 g kg⁻¹ | |
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EU dossier - 1,5-diphenylcarbonohydrazide at 0.0555 g kg⁻¹; 2-phenylacetohydrazide at 0.3 g kg⁻¹; phenylhydazine at 0.01 g kg⁻¹; benzene at 0.05 g kg⁻¹ | |
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Synthetic | |
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Protectant with residual activity. Respiration inhibitor (QoL fungicide). Inhibits fungal mitochondrial respiration (at complex III), resulting in decreased ATP production. It is active against zoospore germination and mycelial growth. | |
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131807-57-3 | |
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603-520-1 | |
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594 | |
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113202 | |
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213032 | |
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612-206-00-3 | |
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374.39 | |
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rac-(5R)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione | |
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(RS)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione | |
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5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-2,4-oxazolidinedione | |
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- | |
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- | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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11 | |
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- | |
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Pale cream, odourless powder |
Formulations |
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Often formulated as an aqueous suspo-emulsion (SC) |
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0.059 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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274000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
- | ||||||||
13300 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Toluene5 = Verified data used for regulatory purposes |
- | |||||||||
48 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Hexane5 = Verified data used for regulatory purposes |
- | |||||||||
125000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | |||||||||
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141.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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Decomposes before boiling | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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275 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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4.47 X 1004 | Calculated | - | |||||||
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4.65 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | |||||||
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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1.31 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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Not applicable | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
No dissociation | |||||||||||
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0.00064 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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4.06 X 10-03 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-volatile | ||||||||
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Negligible | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | |||||||
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Negligible | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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231nm = 553, shoulder at 275-280nm, no absorption after 290nm | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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73.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Degradation |
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41.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately persistent | |||||||
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41.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately persistent | ||||||||
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20 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Non-persistent | ||||||||
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152 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Persistent | ||||||||
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- | - | - | ||||||||
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- | - | - | ||||||||
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2015 EU Dossier Lab studies DT₅₀ range 8.0-104.3 days, DT₉₀ range 27.5-214 days | ||||||||||
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12.3 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Grape berries, n=1 | ||||||||||
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9.8 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 6.3-18.0 days, 5 field & undercover grown crops, various matrices, n=6 | ||||||||||
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1.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | |||||||
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- | ||||||||||
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2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | |||||||
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pH sensitive: DT₅₀ 41 days at pH 5, 1.5 hours at pH 9 all at 25 °C | ||||||||||
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0.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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52.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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3847 | ||||||||||
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2015 EU dossier Kd range 23.4-89.1 mL g⁻¹, Koc range 3307-4950 mL g⁻¹, soils=3 | ||||||||||
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40.98 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) (2015 EU dossier)5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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1455 | ||||||||||
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0.832 | ||||||||||
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EU 2015 dossier Kf range 4.5-127.0 mL g⁻¹, Kfoc range 587-3414 mL g⁻¹, Soils=4 | ||||||||||
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No |
Fate indices |
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1.09 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2.04 X 10-02 | Calculated | - | |||||||||||||||||||||||||
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- | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Slightly mobile | Calculated | - | ||||||||||||||||||||||||||
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2.263 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method4 = Verified data |
Below the level of concern for long-range air transport | ||||||||||||||||||||||||||
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3000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Threshold for concern | |||||||||||||||||||||||||
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Not available | - |
Known soil metabolites |
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Major fraction | 0.111 | - | |||||
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Major fraction | 0.162 | - | |||||
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- | - | Photolysis | |||||
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Minor fraction | - | - | |||||
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- | - | DT50 soil = 13.0 days; Kfoc=22482 mL/g |
Known groundwater metabolites |
None
Other known metabolites |
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formic acid (Ref: IN-02317) | - | Water (Photolysis) | - | ||||
1,2-benzenediol (Ref: IN-03492) | - | Hydrolysis; Water (Photolysis); Rat | - | ||||
4-aminophenyl acetate (Ref: IN-BY759) | - | Rat | - | ||||
4-aminophenyl (Ref: IN-CH490) | - | Animal | - | ||||
oxalic acid (Ref: IN-DI994) | - | Water (Photolysis) | - | ||||
benzenamine (Ref: IN-E0933) | - | Animal | - | ||||
3-aminophenol (Ref: IN-EK332) | - | Hen | - | ||||
5-methyl-5-(4-phenoxyphenyl)-2,4-oxazolidinedione (Ref: IN-KF015) | - | Water (Photolysis); Plant; Hen | - | ||||
potassium 2-phenylhydrazinecarboxylate (Ref: IN-KT983) | - | Hydrolysis | - | ||||
5-{4-)4-hydroxyphenoxy)phenyl]-5-methyl-2,4-oxazolidinedione (Ref: IN-ZK007) | - | Animal | - | ||||
3-[(4-hydroxyphenyl)amino]-5-methyl-5-(4-phenoxyphenyl)-2,4-oxazoldinediol (Ref: IN-KZ532) | - | Plant; Animal | - | ||||
5-[4-(4-hydroxyphenoxy)phenyl]-3-[(4-hydroxyphenyl)amino]-5-methyl-2,4-oxazolidinedione (Ref: IN-KZ534) | - | Plant; Animal | - | ||||
N-phyenylacetamide (Ref: IN-M0278) | - | Goat | - | ||||
Phenol (Ref: IN-M0371) | - | Hydrolysis; Water (Photolysis) | - | ||||
Ref: IN-ME338 | - | Hen | - | ||||
alpha-hydroxy-4-(4-hydroxyphenoxy)-alpha-methyl-4- phenoxybenzeneaceticacid (Ref: IN-ML436) | - | Rat; Hen | - | ||||
alpha-hydroxy-4-(4-hydroxyphenoxy)-alpha-methylbenzeneacetic acid 2-phenylhydrazide (Ref: IN-LM815) | - | Plant; Animal | - | ||||
Ref: IN-MN967 | - | Rat | - | ||||
Ref: IN-MP821 | - | Plant; Hen | - | ||||
Ref: IN-MQ607 | - | Goat | - | ||||
Ref: IN-MQ608 | - | Hen | - | ||||
Ref: IN-MQ609 | - | Hen | - | ||||
Ref: IN-MQ610 | - | Hen | - | ||||
Ref: IN-MQ613 | - | Plant | - | ||||
benzeneacetic acid (Ref: IN-JL856) | - | Water (Hydrolysis, Photolysis); Plant; Animal | - | ||||
1-(4-phenoxyphenyl_ethanone (Ref: IN-H3310) | - | Water (Hydrolysis); Water-Sediment systems; Plant; Animal | - | ||||
Ref: IN-MN968 | - | Hydrolysis | - | ||||
4-phenoxybenzoic acid (Ref: IN-H3310) Note: DT50 soil = 0.6 days; Kfoc=2157 mL/g |
- | Water (Hydrolysis) | - | ||||
N-(4-hydroxyphenol)acetamide (Ref: IN-00915) | - | Animal | - | ||||
fumaric acid (Ref: IN-02162) | - | Water (Photolysis) | - |
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Terrestrial ecotoxicology |
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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3.3 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
High | |||||||
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- | - | |||||||||
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> 44.7 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat Reproductive NOAEL5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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> 2250 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 5620 mg kg feed⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus5 = Verified data used for regulatory purposes |
- | ||||||||
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124.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus NOAEL5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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235 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida corr5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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8.15 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida corr5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 1.44 mg kg⁻¹ soil |
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> 300 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Blackgrass Lambsquarter Chickweed Velvetleaf & others5 = Verified data used for regulatory purposes Vegetative vigour, ER₅₀ as g ha⁻¹ |
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> 201 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Corn Onion Soybean Sugarbeet & others5 = Verified data used for regulatory purposes Seedling emergence, ER₅₀ as g ha⁻¹ |
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> 25 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
Moderate | |||||||
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> 1.0 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera max conc due to solubility limit4 = Verified data |
Moderate | ||||||||
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0.43 | P4 P = Other non-EU, UK or US Governments and Regulators Apis mellifera 120 hr Larvae4 = Verified data |
High | ||||||||
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> 446 | P5 P = Other non-EU, UK or US Governments and Regulators Coccinella septempunctata5 = Verified data used for regulatory purposes |
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> 446 | P5 P = Other non-EU, UK or US Governments and Regulators Chrysoperla carnea/i>5 = Verified data used for regulatory purposes |
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> 2240 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi5 = Verified data used for regulatory purposes |
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> 2240 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri5 = Verified data used for regulatory purposes |
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0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Poecilus cupreus5 = Verified data used for regulatory purposes |
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Aquatic ecotoxicology |
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0.011 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
High | ||||||||
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0.0014 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
High | ||||||||
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1.24 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio3 = Unverified data of known source |
Moderate | ||||||||
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0.033 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.0037 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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- | - | - | ||||||||
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- | - | - | ||||||||
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- | - | - | ||||||||
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> 0.007 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
High | ||||||||
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- | - | - | ||||||||
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0.0081 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Lemna gibba5 = Verified data used for regulatory purposes |
High | ||||||||
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0.00308 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Pseudokirchneriella subcapitata5 = Verified data used for regulatory purposes |
High | ||||||||
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- | - | - | ||||||||
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- | - | - |
|
- | - | - |
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General |
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|
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|
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High (class III) | - | - | ||||||||
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
- | ||||||||
|
> 5.3 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat 4 hr5 = Verified data used for regulatory purposes |
- | ||||||||
|
- | - | - | ||||||||
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0.006 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
|
0.1 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
|
- | - | - | ||||||||
|
0.0024 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
|
0.4-2.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) concentration dependent5 = Verified data used for regulatory purposes |
- | ||||||||
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- | - | - | ||||||||
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Minimal risk from dietary exposure Risk assessment indicates ARfD would not normally be execeeded |
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Risk of exposure acceptable under label recommendations for use for personal protection clothing and equipment | ||||||||||
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- | ||||||||||
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- | - | - |
Health issues |
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Splene, liver & red blood cell toxicant May cause long term eye damage from repeated exposure Cataractogenic to dogs following repeat dose - human relevance cannot be ruled out |
Handling issues |
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Not explosive or oxidising Not explected to auto-ignite, Not highly flammable IMDG Transport Hazard Class 9 |
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Health: H373 Environment: H400, H410 |
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U (Unlikely to present an acute hazard) | |||
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UN3077 | |||
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Packaging Group III (minor danger) | |||
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Relatively unstable at ambient temperatures, Products should remain within specifications for at least 2 years when stored at ambient temperature |
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famoxadone | ||
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famoxadone | ||
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Famoxadone | ||
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famoxadon | ||
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famoxadone | ||
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famoxadona | ||
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famoxadone | ||
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famoksadon | ||
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famoxadon | ||
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famoxadon | ||
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famoxadon | ||
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- |
Record last updated: | 31/10/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |