Cis-flurochloridone |
Last updated: 31/10/2024 |
(Not known by any other names) |
SUMMARY |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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Flurochlorididone is a pre-emergence herbicide used to control a range of weeds in umbelliferous crops, cereals and potatoes | |
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Annual broad-leaved weeds; Grasses | |
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Cotton; Potatoes; Cereals including winter rye, winter wheat; Sunflowers; Umbelliferous crops including carrot, celery, celeriac, parsnip | |
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Current | |
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1985, introduced |
UK regulatory status |
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Not approved | ||
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Withdrawn | ||
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No data |
EC Regulation 1107/2009 (repealing 91/414) |
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Approved (as the isomer mixture) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Austria/Hungary | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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15/03/2026 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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South Africa |
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Chemical structure |
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This record refers to the cis-isomer of flurochloridone. Commercial flurochloridone normally refers to a mixture trans and cis isomers in the ratio 3:1. The trans-isomers have the greater herbicidal activity. | |
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C₁₂H₁₀Cl₂F₃NO | |
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Yes |
General status |
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Herbicide | |
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Pyrrolidine herbicide; Organochloride herbicide; Organofluoride herbicide | |
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Synthetic | |
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Selective, absorbed by roots and stem. Bleaching - Carotenoid biosynthesis inhibitor. | |
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430 | |
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312.12 | |
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rac-(3R,4R)-3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one | |
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(3RS,4RS)-3-chloro-4-(chloromethyl)-1-(α,α,α-trifluoro-m-tolyl)-2-pyrrolidone | |
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cis-3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]-2-pyrrolidinone | |
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F1 | |
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Not applicable | |
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Not applicable | |
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Formulations |
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Often supplied as an emulsifiable concentrate |
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11.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.06 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility | ||||||||
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7.0 X 10-04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-volatile | ||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 1000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as flurochloridone4 = Verified data |
Moderate | ||||||||
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Aquatic ecotoxicology |
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0.13 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chironomus riparius5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.031 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Lemna gibba5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.00088 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Desmodesmus subspicatus5 = Verified data used for regulatory purposes |
High | ||||||||
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0.00014 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Desmodesmus subspicatus5 = Verified data used for regulatory purposes |
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General |
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> 1000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as flurochloridone4 = Verified data |
Moderate | ||||||||
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5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as Flurochloridone5 = Verified data used for regulatory purposes |
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> 4.82 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat 4 hr (nose only) as Flurochloridone5 = Verified data used for regulatory purposes |
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0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=100 as flurochloridone5 = Verified data used for regulatory purposes |
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0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=500 as flurochloridone5 = Verified data used for regulatory purposes |
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0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=500 as flurochloridone5 = Verified data used for regulatory purposes |
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0.04 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat SF=500 as flurochloridone5 = Verified data used for regulatory purposes |
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1.3-23.8 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) concentration dependent5 = Verified data used for regulatory purposes |
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No unacceptable risks to bystanders identified | |||||||||
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No unacceptable risks to operators or other workers identified for intended uses Soil residues may present slight risk to field workers |
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>89% of dose eliminated within 72 hrs in urine and faeces | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Health issues |
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Possible liver and testes toxicant |
Handling issues |
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Not explosive or oxisiding Not expected to auto-ignite; Not highly flammable |
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Health: H302, H317, H360f Environment: H400, H410 |
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III (Slightly hazardous) | |||
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cis-flurochloridone | ||
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Record last updated: | 31/10/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |