Propylene glycol |
Last updated: 18/01/2024 |
(Also known as: methylethyl glycol; E1520) |
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A synthetic food and feed additive | |
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Current | |
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Used for the treatment of acetonaemia and ketosis, to aid the delivery of skin healing medication as well as a general purpose feed additive | |
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Dogs; Cattle; Sheep; Horses |
Approval status |
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Approved | |
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Approved |
Chemical structure |
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C₃H₈O₂ | |
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CC(CO)O | |
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No data | |
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DNIAPMSPPWPWGF-UHFFFAOYSA-N | |
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InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3 | |
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Yes |
General status |
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Feed additive | |
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Solvent | |
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Unclassified substance | |
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Synthetic | |
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Inert | |
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57-55-6 | |
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200-338-0 | |
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068603 | |
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Alimentary tract & metabolism: Other alimentary tract & metabolism products | |
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QA16QA01 | |
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No | |
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Allowed substance (Table 1: All food producing species) | |
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76.09 | |
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propane-1,2-diol | |
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1,2-propanediol | |
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Colourless viscous liquid |
Formulations |
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Dermisol Cream | Zoetis UK Ltd | UK National authorisation | Prescription only medicine to be authorised by suitably qualified person (POM-VPS) | ||||||
Forketos Oral Solution | Alfasan Nederland B.V. | UK National authorisation | Authorised veterinary medicine for general sale (AVM-GSL) | |||||||
Ketosaid Oral Solution | Norbrook Laboratories Ltd | UK National authorisation | Authorised veterinary medicine for general sale (AVM-GSL) | |||||||
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Available in a variety of formulations including creamss and ointments, oral drenches and oral solutions |
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1000000 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) at 25 °C3 = Unverified data of known source |
High | ||||||||
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Miscible | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Ethanol3 = Unverified data of known source |
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Miscible | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Acetone3 = Unverified data of known source |
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Miscible | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Chloroform3 = Unverified data of known source |
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Miscible | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Ether3 = Unverified data of known source |
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-59 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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1.20 X 10-01 | Calculated | - | |||||||
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-0.92 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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1.036 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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14.9 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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Very weak acid | |||||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 20000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
Low | ||||||||
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2080 | Q3 Q = Miscellaneous data from online sources Colinus virginianus3 = Unverified data of known source |
Low | ||||||||
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Aquatic ecotoxicology |
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710 | Q2 Q = Miscellaneous data from online sources Pimephales promelas2 = Unverified data of unknown source |
Low | ||||||||
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10000 | Q3 Q = Miscellaneous data from online sources Daphnia magna3 = Unverified data of known source |
Low | ||||||||
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General |
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Low (class I) | - | - | ||||||||
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> 20000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
Low | ||||||||
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20800 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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Mainly eliminated unchanged in the urine | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Possible liver and kidney toxicant May cause seizures, coma, arrhythmias & cardiorespiratory arrest |
Handling issues |
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Flammable | |||
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Not listed (Not listed) | |||
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propylene glycol | ||
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1,2-Propylenglykol | ||
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propylenowo-glikolowy | ||
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Record last updated: | 18/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |