Prallethrin (Ref: OMS 3033) |
Last updated: 22/08/2024 |
(Also known as: S-4068SF; d-prallethrin) |
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A synthetic pyrethroid with fast knock-down activity against various insect pests | |
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Current | |
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1988, introduced Japan | |
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Use to control insect pests on domestic pets and pet bedding | |
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Dogs; Cats |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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Prallethrin is a complex chiral molecule. The technical material is an isomeric mixture of 8 stereoisomers but consists mainly of [1R,trans; S] and [1R,cis; S] isomers in a ratio of approximately 4:1.. | |
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C₁₉H₂₄O₃ | |
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CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC#C | |
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SMKRKQBMYOFFMU-UHFFFAOYSA-N | |
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InChI=1S/C19H24O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h1,9,14,16-17H,8,10H2,2-6H3/t14-,16?,17+/m0/s1 | |
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Yes |
General status |
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Insecticide | |
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Pyrethroid insecticide; Pyrethroid ester insecticide | |
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>900 g/Kg | |
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Synthetic | |
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Contact, with rapid knock down effect, acts on the insects nervous system. Sodium channel modulator. | |
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[Sodium channel, Modulator] | |
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23031-36-9 | |
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245-387-9 | |
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743 | |
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128722 | |
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9839306 | |
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607-431-00-9 | |
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None allocated | |
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No | |
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300.40 | |
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(1E)-2-methyl-4-oxo-3-(prop-2-yn-1-yl)cyclopent-2-en-1-yl (1E,3E)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate | |
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(RS)-2-methyl-4-oxo-3-prop-2-ynylcyclopent-2-enyl (1RS,3RS;1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate | |
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2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate | |
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PAN listed Highly Hazardous Chemical | |
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Yellowish-brown oily liquid |
Formulations |
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8.03 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) 4 = Verified data |
Low | ||||||||
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500000 | L3 L = Pesticide manuals and hard copy reference books / other sources Hexane3 = Unverified data of known source |
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500000 | L3 L = Pesticide manuals and hard copy reference books / other sources Methanol3 = Unverified data of known source |
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500000 | L3 L = Pesticide manuals and hard copy reference books / other sources Xylene3 = Unverified data of known source |
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-25 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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313.5 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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139 | E3 E = Manufacturers safety data sheets (Pensky-Martens closed test)3 = Unverified data of known source |
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3.09 X 1004 | Calculated | - | |||||||
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4.49 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) 4 = Verified data |
High | ||||||||
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1.03 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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0.64 | R4 R = Peer reviewed scientific publications 25°C4 = Verified data |
Low volatility. If applied directly to plants, drift is a concern & mitigation is advisable | ||||||||
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0.010 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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460 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat4 = Verified data |
Moderate | ||||||||
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> 2000 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Anas platyrhynchos4 = Verified data |
Low | ||||||||
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0.026 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Apis mellifera4 = Verified data |
High | |||||||
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Aquatic ecotoxicology |
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0.012 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Oncorhynchus mykiss4 = Verified data |
High | ||||||||
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> 0.003 | P4 P = Other non-EU, UK or US Governments and Regulators Oncorhynchus mykiss 61 day4 = Verified data |
High | ||||||||
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0.0062 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Daphnia magna4 = Verified data |
High | ||||||||
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> 0.00065 | P4 P = Other non-EU, UK or US Governments and Regulators Daphnia magna4 = Verified data |
High | ||||||||
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General |
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Intermediate (class II) | - | - | ||||||||
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460 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat4 = Verified data |
Moderate | ||||||||
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5000 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat4 = Verified data |
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0.29 | B4 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) Rat 4 hr4 = Verified data |
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Health issues |
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Toxic if ingested or inhaled |
Handling issues |
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IMDG Transport Hazard Class 6.1 | |||
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Health: H302, H331 Environment: H400, H410 |
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II (Moderately hazardous) | |||
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UN2811 | |||
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Packaging Group I (great danger) | |||
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prallethrin | ||
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praletrin | ||
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Record last updated: | 22/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |