Fluazuron (Ref: CGA 157419) |
Last updated: 09/01/2024 |
(Also known as: ixodicide) |
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Insect growth regulator and broad spectrum antiparasitic substance | |
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Used to control ticks in livestock, especially cattle | |
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Farmed livestock |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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C₂₀H₁₀Cl₂F₅N₃O₃ | |
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C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2)Cl)OC3=C(C=C(C=N3)C(F)(F)F)Cl)F | |
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No data | |
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YOWNVPAUWYHLQX-UHFFFAOYSA-N | |
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InChI=1S/C20H10Cl2F5N3O3/c21-11-5-4-10(29-19(32)30-17(31)16-13(23)2-1-3-14(16)24)7-15(11)33-18-12(22)6-9(8-28-18)20(25,26)27/h1-8H,(H2,29,30,31,32) | |
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Yes |
General status |
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Acarcide, Insecticide, Ioxodicide | |
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Benzoylphenyl urea | |
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Synthetic | |
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Chitin synthesis inhibitor. Treated immature ticks are unable to moult to the next stage, and no larvae will hatch from eggs laid by treated females | |
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[Chitin synthesis, Inhibitor] | |
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86811-58-7 | |
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None allocated | |
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No | |
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Allowed substance (Table 1: Bovine) | |
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506.21 | |
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1-[4-chloro-3-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenyl]-3-(2,6-difluorobenzoyl)urea | |
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N-[[[4-chloro-3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]amino]carbonyl]-2,6-difluorobenzamide | |
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White to pale pink fine crystalline powder |
Formulations |
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0.02 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | ||||||||
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2400 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Methanol3 = Unverified data of known source |
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900 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Isopropanol3 = Unverified data of known source |
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700 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) n-Octanol3 = Unverified data of known source |
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30000 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Hexane3 = Unverified data of known source |
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219 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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219 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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1.26 X 1005 | Calculated | - | |||||||
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5.1 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
High | ||||||||
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1.59 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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1.2 X 10-07 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Low volatility | ||||||||
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3.04 X 10-06 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known soil and groundwater metabolites |
None
Other known metabolites |
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3-[3-(3-chloro-5-trifluoromethyl-2-pyridinyloxy)-4-chloro-6-hydroxyphenyl]urea | - | Rats | - |
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Terrestrial ecotoxicology |
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> 5000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat4 = Verified data |
Low | ||||||||
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> 2000 | L3 L = Pesticide manuals and hard copy reference books / other sources Anas platyrhynchos3 = Unverified data of known source |
Low | ||||||||
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1000 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderate | ||||||||
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Aquatic ecotoxicology |
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15 | L3 L = Pesticide manuals and hard copy reference books / other sources Oncorhynchus mykiss3 = Unverified data of known source |
Moderate | ||||||||
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0.0006 | L3 L = Pesticide manuals and hard copy reference books / other sources Daphnia magna3 = Unverified data of known source |
High | ||||||||
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27.9 | L2 L = Pesticide manuals and hard copy reference books / other sources Unknown species2 = Unverified data of unknown source |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 5000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat4 = Verified data |
Low | ||||||||
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200 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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5.99 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat 4 hr3 = Unverified data of known source |
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Mainly eliminated as metabolites in the faeces | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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Health issues |
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No further information available |
Handling issues |
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No information available | |||
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III (Slightly hazardous) | |||
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fluazuron | ||
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fluazuron | ||
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fluazurón | ||
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Record last updated: | 09/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |