Choline chloride |
Last updated: 01/06/2024 |
(Also known as: hepacholine; biocolina; lipotril; choline hydrochloride) |
SUMMARY |
Choline chloride is a plant growth regulator. It is highly soluble in water, is not volatile or persistent in soil systems. Based on its physico-chemical properties it has potential to leach to groundwaters. It tends not to be highly toxic to biodiversity although available data is limited. Choline chloride has a low mammalian toxicity and whilst it may be a skin and eye irritant no evidence has been found to suggest exposure may cause chronic health conditions. |
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Quarternary ammonium compound which is an essential nutrient for normal animal growth and performance | |
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Current | |
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2016, registration US | |
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Used as a poultry growth accelerator administered as a feed additive. Acts as a liver detoxifier. Mmay also be used to treats epilepsy and cognitive dysfunction | |
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Chickens; Turkeys; Dogs |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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None | |
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C₅H₁₄ClNO | |
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C[N+](C)(C)CCO.[Cl-] | |
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- | |
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SGMZJAMFUVOLNK-UHFFFAOYSA-M | |
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InChI=1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1S | |
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Yes |
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Common Name | Relationship | Link |
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choline chloride | - |
General status |
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Medicinal drug, Performance enhancer | |
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Quarternary ammonium compound; Animal-derived substance | |
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Natural | |
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Probable enhanced formation of plant hormone abscisic acid (ABA) | |
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67-48-1 | |
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200-65-54 | |
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None allocated | |
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018102/718102, | |
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6209 | |
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No data found | |
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- | |
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None allocated | |
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No | |
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- | |
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139.62 | |
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2-hydroxy-N,N,N-trimethylethan-1-aminium chloride | |
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ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride | |
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(2-hydroxyethyl)trimethylammonium chloride | |
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White hygroscobic crystals |
Formulations |
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650000 | P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
High | ||||||||
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247 | P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
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1.70 X 10-04 | Calculated | - | |||||||
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-3.77 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data |
Low | ||||||||
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1.1 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) 4 = Verified data |
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6.57 X 10-05 | P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Low volatility | ||||||||
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2.06 X 10-11 | P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Non-volatile | ||||||||
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Degradation |
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7 | S1 S = Expert judgement 1 = Estimated data with little or no verification |
Non-persistent | |||||||
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Best available data | ||||||||||
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Stable | P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Stable | |||||||
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Stable under normal environmental conditions | ||||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Very mobile | |||||||
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0 | ||||||||||
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Estimated | ||||||||||
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Fate indices |
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5.07 | Calculated | High leachability | ||||||||||||||||||||||||||
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0.59 | Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Low potential | |||||||||||||||||||||||||
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Not available | - |
Known metabolites |
None
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Terrestrial ecotoxicology |
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3400 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat4 = Verified data |
Low | ||||||||
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Aquatic ecotoxicology |
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100 | Q2 Q = Miscellaneous data from online sources Oncorhynchus mykiss2 = Unverified data of unknown source |
Moderate | ||||||||
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349 | P4 P = Other non-EU, UK or US Governments and Regulators Daphnia magna4 = Verified data |
Low | ||||||||
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1000 | Q2 Q = Miscellaneous data from online sources Pseudokirchneriella subcapitata2 = Unverified data of unknown source |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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3400 | AC4 AC = EC Joint Research Centre ESIS European Chemical Substance Information Systems including EINECS, now integrated with the database provided by the European Chemicals Agency (ECHA) (click here ) Rat4 = Verified data |
Low | ||||||||
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Possible exposure via skin contact and inhallation | ||||||||||
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Health issues |
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May cause hypotension May cause nausea and diarrhoea Gastrointestinal toxicant May cause dermatitis |
Handling issues |
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Prevent generation of dust Hygroscopic |
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Health: H315, H319, H335 Environment: H400 |
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Not listed (Not listed) | |||
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choline chloride | ||
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chloride de choline | ||
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Cholinchlorid | ||
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cholin klorid | ||
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cloruro di colina | ||
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cloruro de colina | ||
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chlorek choliny | ||
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Record last updated: | 01/06/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |