Linalool |
Last updated: 28/08/2024 |
(Also known as: linalol; para-linalool; linalyl alcohol; licareol; coriandrol) |
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A plant derived oil used for parasite control and for its mild sedative properties | |
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Current | |
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1985, first approved for use USA | |
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Used mainly as an insect repellent and for the control of fleas. | |
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Dogs; Cats |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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Linalool has two enantiomers (R)- (-)-linalool and (S)- (+)-Linalool | |
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C₁₀H₁₈O | |
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CC(=CCCC(C)(C=C)O)C | |
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No data | |
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CDOSHBSSFJOMGT-UHFFFAOYSA-N | |
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InChI=1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3 | |
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Yes |
General status |
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Insecticide | |
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Plant-derived substance | |
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>99% | |
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- | |
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Natural | |
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Contact poision for insects causing a neurotoxic effect | |
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[Glutamatergic transmission, Antagonist], [Glutamate [NMDA] receptor subunit 3A, Antagonist] | |
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78-70-6 | |
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201-134-4 | |
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128838 | |
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Ectoparasiticides: Various repellents | |
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None allocated | |
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No | |
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154.25 | |
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- | |
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3,7-dimethylocta-1,6-dien-3-ol | |
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2,6-dimethyl-2,7-octadien-6-ol | |
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FLAVIS no. 02.013 | |
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Colourless, clear liquid |
Formulations |
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Holiday Concentrated Dog and Cat Shampoo | Wellmark International Ltd | Not licensed | Not licensed | ||||||
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1589 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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<25 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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194 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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78.3 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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1.91 X 1003 | Calculated | - | |||||||
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3.28 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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1.46 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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1.460 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Low risk | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Based on LogP < 34 = Verified data |
Low risk | |||||||||||||||||||||||||
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 1700 | E3 E = Manufacturers safety data sheets Rat3 = Unverified data of known source |
Moderate | ||||||||
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> 5620 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Colinus virginianus4 = Verified data |
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> 200 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Unknown species predicted3 = Unverified data of known source |
Moderate | ||||||||
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> 100 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | |||||||
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Aquatic ecotoxicology |
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> 28.8 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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< 3.5 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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36.7 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Unknown species3 = Unverified data of known source |
Moderate | ||||||||
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88.3 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Scenedesmus subspicatus4 = Verified data |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 1700 | E3 E = Manufacturers safety data sheets Rat3 = Unverified data of known source |
Moderate | ||||||||
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5610 | Q3 Q = Miscellaneous data from online sources Rabbit3 = Unverified data of known source |
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2.95 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
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Intraperitoneal LD₅₀ = 340 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Mouse3 = Unverified data of known source |
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Subcutaneous LD₅₀ = 1470 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Mouse3 = Unverified data of known source |
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Mainly excreted in urine and bile | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Some texts claim it is an anti-cancer agent May cause respiratory and digestive tract irritation |
Handling issues |
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Combustable liquid and vapour | |||
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Not listed (Not listed) | |||
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linalool | ||
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Record last updated: | 28/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |