Trenbolone acetate (Ref: RU 1697) |
Last updated: 25/04/2024 |
(Also known as: TbA; 17beta-trenbolone Acetate) |
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An anabolic steroid used in veterinary medicine | |
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Current | |
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1987, first registrations | |
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Used in many countries to increase muscle mass and appetite of livestock especially cattle | |
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Cattle |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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Isomeric mixture | |
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C₂₀H₂₄O₃ | |
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CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2O | |
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C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O | |
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MEHHPFQKXOUFFV-OWSLCNJRSA-N | |
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InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3/t15-,16+,17+,18+/m1/s1 | |
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Yes |
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Common Name | Relationship | Link |
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17beta-trenbolone | Parent |
General status |
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Steroid, Medicinal drug, Hormone, Growth promotor | |
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Unclassified substance | |
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Synthetic | |
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Thought to significantly increase the circulating levels of IGF-1 and decreases the normal loss of muscle in sedentary animals | |
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[Androgen receptor, Agonist] | |
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10161-33-8 | |
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Anabolic steroids | |
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QA12A | |
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UK: Class C, Schedule 4 Pt2 | |
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312.39 | |
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3-oxo-17-β-hydroxy-4,9,11-estratriene acetate | |
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Pale yellow crystalline powder |
Formulations |
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Synovex Choice | Fort Dodge Animal Health | Not licensed | Not licensed | ||||||
Revalor-S | MSD Animal Health | Not licensed | Not licensed | |||||||
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17 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | ||||||||
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95 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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1.29 X 1002 | Calculated | - | |||||||
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2.11 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | ||||||||
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Degradation |
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0.3 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
Non-persistent | |||||||
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Literature states that DT₅₀ ranges from a few hours to 0.5 days | ||||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
Very mobile | |||||||
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3.08 | ||||||||||
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Isomer dependent Koc range 2.77-3.38 mL g⁻¹ | ||||||||||
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Fate indices |
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-1.84 | Calculated | Low leachability | ||||||||||||||||||||||||||
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Known soil and groundwater metabolites |
None
Other known metabolites |
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trenbolone-17beta | - | Animals; Human | - | ||||
trendione | - | Animals; Human | - | ||||
trenbolone-17alpha | - | Animals; Human | - |
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Terrestrial ecotoxicology |
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> 5000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
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Aquatic ecotoxicology |
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0.00005 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Pimephales promelas4 = Verified data |
High | ||||||||
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General |
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High (class III) | - | - | ||||||||
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> 5000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
Low | ||||||||
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Mainly eliminated unchanged via excreta and bile | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Health issues |
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Potentially harmful to reproductive organs Possible liver toxicant |
Handling issues |
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Reactive with acids, alkalis and oxidising agents | |||
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Not listed (Not listed) | |||
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Not regulated | |||
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trenbolone acetate | ||
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Trembolona | ||
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Record last updated: | 25/04/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |