Arsenous oxide |
Last updated: 22/08/2024 |
(Also known as: arsenious acid; arsenic trioxide; arsenic (III) oxide; arsenic (3+) oxide; diarsenic trioxide; arsenic sesquioxide) |
SUMMARY |
Arsenous oxide was once used as a rodenticide and in sheep dips. It is no longer approved for use in most countries due to its toxicity to humans and the environment. Arsenous oxide is highly toxic to all mammals, is a carcinogen, a reproduction toxin and highly corrosive. It is quite soluble in aqueous solution but practically insoluble in most organic solvents. It is also toxic to most fauna and flora. |
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A now obsolete antiparasitic agent | |
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Considered obsolete but may be available in some countries | |
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circa 16th century, introduced | |
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Used, historically, in sheep dips | |
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Sheep |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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None | |
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As₂O₃ | |
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[O-2].[O-2].[O-2].[As+3].[As+3] | |
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- | |
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QTLQKAJBUDWPIB-UHFFFAOYSA-N | |
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InChI=1S/2As.3O/q2*+3;3*-2 | |
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Yes |
General status |
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Antiparasitic | |
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Inorganic compound | |
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Synthetic | |
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Inhibits sulfhydral enzymes | |
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[Sulfhydral enzymes, Inhibitor] | |
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1327-53-3 | |
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28380-38-3 | |
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215–481–4 | |
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250 | |
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- | |
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14888 | |
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033-003-00-0 | |
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Not allocated | |
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No | |
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- | |
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197.84 | |
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diarsenic trioxide | |
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diarsenic trioxide | |
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arsenic oxide | |
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PAB Bad Actor Chemical | |
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- | |
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Colourless crystalline solid |
Formulations |
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17000 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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Insoluble | L3 L = Pesticide manuals and hard copy reference books / other sources Chloroform3 = Unverified data of known source |
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Insoluble | L3 L = Pesticide manuals and hard copy reference books / other sources Diethyl ether3 = Unverified data of known source |
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Insoluble | L3 L = Pesticide manuals and hard copy reference books / other sources Ethanol3 = Unverified data of known source |
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272 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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465 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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20 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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Aquatic ecotoxicology |
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> 18.1 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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2.65 | P3 P = Other non-EU, UK or US Governments and Regulators Oncorhynchus mykiss 10 day3 = Unverified data of known source |
Moderate | ||||||||
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> 12.9 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio4 = Verified data |
Moderate | ||||||||
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> 3.85 | P4 P = Other non-EU, UK or US Governments and Regulators Daphnia magna4 = Verified data |
Moderate | ||||||||
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1.85 | P4 P = Other non-EU, UK or US Governments and Regulators Daphnia magna4 = Verified data |
Moderate | ||||||||
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10 | L3 L = Pesticide manuals and hard copy reference books / other sources Lemna paucicostata3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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20 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | ||||||||
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Intraperitoneal LD₅₀ = 871 mg kg⁻¹ | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
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Highly toxic - PPE/PPC essential | ||||||||||
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Eliminated in urine | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Extremely toxic IARC Group 1 carcinogen Will cause a number of severe symptoms if ingested including chest pains, dizziness, breathing problems and weakness |
Handling issues |
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Dissolves in alkali to form toxic arsenites Corrosive |
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Ia (Extremely hazardous) | |||
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arsenous oxide | ||
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oxyde arsenieux | ||
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Record last updated: | 22/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |