Boldenone acetate |
![]() Last updated: 16/09/2025 |
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(Also known as: boldenone 17-acetate) |
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An anabolic steriod veterinary drug applied intramuscularly for its anabolic properties | |
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Used for weight gain and greater efficiency of feed conversion | |
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Horses; Elephants |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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Boldenone exhibits stereoisomerism, specifically chirality, due to the presence of multiple chiral centres in its steroidal structure. As a derivative of testosterone, boldenone’s core is the androstane skeleton, which includes several carbon atoms bonded in a rigid, fused ring system. The molecule contains six stereocentres at positions C8, C9, C10, C13, C14, and C17, each contributing to its three-dimensional configuration. | |
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C₂₁H₂₈O₃ | |
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CC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)C=CC34C)C | |
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CC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)C | |
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KPCDGGNHYODURF-PXQJOHHUSA-N | |
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InChI=1S/C21H28O3/c1-13(22)24-19-7-6-17-16-5-4-14-12-15(23)8-10-20(14,2)18(16)9-11-21(17,19)3/h8,10,12,16-19H,4-7,9,11H2,1-3H3/t16-,17-,18-,19-,20-,21-/m0/s1 | |
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Yes |
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Common Name | Relationship | Link |
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boldenone acetate | - | ![]() |
General status |
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Hormone | |
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Hormone | |
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Synthetic | |
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Boldenone work by stimulation of receptors molecule in muscle cells, which activate specific genes to produce proteins | |
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[Androgen receptor, Agonist] | |
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2363-59-9 | |
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219-112-8 | |
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102247 | |
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Anabolic agents for systemic use | |
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QA14 | |
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UK: Class C, Schedule 4 Pt2 | |
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328.4 | |
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[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] acetate | |
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DEA Schedule III | |
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Powdery solid | |
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Commercial |
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Current | |||
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1949, patented; 1950s, experimental animal use; 2003, strict regulatory scrutiny & usage controls | |||
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Supplied as an oil suspension | |||
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Boldenone acetate is synthesised by first producing boldenone base, typically through the chemical transformation of androstenedione using a two-step process: etherification followed by reduction and hydrolysis. In the etherification step, androstenedione is reacted with triethyl orthoformate and a catalyst like pyridine hydrobromide in ethanol to form an etherate intermediate. This intermediate is then reduced using sodium borohydride in methanol, yielding crude boldenone. Once purified, the boldenone base undergoes esterification with acetic acid or acetic anhydride in the presence of a coupling agent such as dicyclohexylcarbodiimide or p-toluenesulfonic acid, forming boldenone acetate. | |||
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Published GHG data is not available for most pharmaceuticals. However, according to industry, global averages suggest producing 1 kg of a typical active pharmaceutical ingredient can range from 10 to 100 kg CO₂e for small molecule drugs and potentially up to 1000 kg CO₂e for complex biologicals such as vaccines, depending on the drug type, its formulation, complexity of synthesis, solvent recovery, and energy sources used. |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Fate indices |
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Known metabolites |
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Terrestrial ecotoxicology |
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Urinary excretion | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
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Health issues |
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Possible liver & kidney toxicant Can be absorbed through the skin Encourages the development of masculine characteristics CPL adta: suspeccted carcinogen |
Handling issues |
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May be combustible at high temperatrues May react with oxidising agents |
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Health: H305, H351 | |||
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Not listed (Not listed) | |||
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boldenone acetate | ||
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Record last updated: | 16/09/2025 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |