Chloramine-T |
Last updated: 24/10/2024 |
(Also known as: chloramine-T anhydrous; N-chlorotosylamide, sodium salt; tosylchloramide) |
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A chlorinated and deprotonated sulfonamide that is an effective broad spectrum antibacterial substance with veterinary applications | |
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Current | |
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early- to mid-1990's, first registered USA | |
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Used to control Gill Flukes, Body Flukes, White Spot, Costia and Bacterial Gill Disease, as a disinfectnt and for the reduction of pathogenic bacterial levels. | |
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Salmonid fish |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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None | |
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C₇H₇ClNNaO₂S | |
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CC1=CC=C(C=C1)S(=O)(=O)[N-]Cl.[Na+] | |
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VDQQXEISLMTGAB-UHFFFAOYSA-N | |
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InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1 | |
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Yes |
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Common Name | Relationship | Link |
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chloramine-T trihydrate | Hydrate |
General status |
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Antibacterial | |
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Antifouling agent, Biocide, Disinfectant, Preservative | |
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Sulphonamide | |
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Synthetic | |
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[Cytochrome P450 2E1, Activator], [Cytochrome P450 1A1, Activator], [Cytochrome P450 2B1, Activator], [DNA, Inhibitor] | |
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127-65-1 | |
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204-854-7 | |
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76502 | |
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3641960 | |
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Dermatologicals; Other antiseptics and disinfectants | |
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QD08AX04 | |
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No | |
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227.64 | |
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sodium; chloro-(4-methylphenyl)sulfonylazanide | |
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- | |
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One used as a herbicide in the USA but was withdrawn mid-1980s | |
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White powder |
Formulations |
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150000 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
High | ||||||||
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Decomposes before melting | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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Decomposes before boiling | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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167 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
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5.01 X 10-02 | Calculated | - | |||||||
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-1.3 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Low | ||||||||
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1.43 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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0.91 | - | Mobile | |||||||
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42 | ||||||||||
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US EPA data: Kd range 0.58-1.04 mL g⁻¹, Koc range 31-52 mL g⁻¹, Soils=3 | ||||||||||
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Fate indices |
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Known soil and groundwater metabolites |
None
Other known metabolites |
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p-toluenesulfonamide Note: LC50 Poecilia reticulata = 31 mg/L; NOEC Daphnia magna = 4.5 mg/L |
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Terrestrial ecotoxicology |
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Q3 Mouse 1100 | - | Moderate | ||||||||
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Aquatic ecotoxicology |
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> 2.8 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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> 2.12 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Ceriodaphnia dubia4 = Verified data |
Moderate | ||||||||
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1.3 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna4 = Verified data |
Moderate | ||||||||
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0.31 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Desmodesmus subspicatus4 = Verified data |
Moderate | ||||||||
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General |
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Q3 Mouse 1100 | - | Moderate | ||||||||
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Intraperitoneal LD₅₀ = 300 mmol/kg | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
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Elimination primarily through the urine | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Exposure may cause burning sensation, coughing, shortness of breath, sore throat and various adverse respiratory conditions |
Handling issues |
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Corrosive May explode on heating above 130°C Combustable IMDG Transport Hazard Clsss 8 |
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Health: H302, H3334 Handling: H334 |
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Not listed (Not listed) | |||
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Packaging group III (minor danger) | |||
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chloramine-T | ||
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Record last updated: | 24/10/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |