Butaphosphan |
Last updated: 13/03/2024 |
(Also known as: butafosfan) |
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An organic source of phosphorus used in veterinary medicine | |
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Used mainly as a supportive treatment of metabolic or reproductive disorders as well as developmental and nutritional disorders | |
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Cattle; Horses; Pigs, Sheep and goats; Dogs; Cats |
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Approved | |
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Approved |
Chemical structure |
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None | |
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C₇H₁₈NO₂P | |
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CCCCNC(C)(C)P(=O)O | |
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WCXWARPXYQCRPP-UHFFFAOYSA-N | |
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InChI=1S/C7H18NO2P/c1-4-5-6-8-7(2,3)11(9)10/h8,11H,4-6H2,1-3H3,(H,9,10) | |
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Yes |
General status |
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Mineral supplement | |
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Phosphonic acid derivative | |
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Synthetic | |
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Mineral supplementation and electrolyte replacement agent | |
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17316-67-5 | |
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241-341-7 | |
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72084 | |
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Alimentary tract and metabolism; mineral supplements; other mineral products, combinations | |
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QA12CX99 | |
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No | |
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179.20 | |
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2-(butylamino)propan-2-ylphosphinic acid | |
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Formulations |
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Butasal Solution | Interchemie Werken De Adelaar Eesti AS | GB National authorisation | Prescription only medicine to be authorised by a veterinarian (POM-V) | ||||||
Vigophos Solution for Injection | Livisto Int'l S.L. | GB National authorisation | Prescription only medicine to be authorised by a veterinarian (POM-V) | |||||||
Butaphosphan | Ashish Life Science Pvt Ltd | Not licensed | Not licensed | |||||||
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Usually formulated, along with cyanocobalamin, as a solution for injection |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
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Terrestrial ecotoxicology |
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16000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Mouse5 = Verified data used for regulatory purposes |
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Aquatic ecotoxicology |
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General |
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High (class III) | - | - | ||||||||
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16000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Mouse5 = Verified data used for regulatory purposes |
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Subcutaneous LD₅₀ = 21000 mg kg⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Mouse5 = Verified data used for regulatory purposes |
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Intravenous LD₅₀ = 10000 mg kg⁻¹ | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Mouse5 = Verified data used for regulatory purposes |
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Elimination is rapid, Within 12 hrs of intravenous administration 70-90% are excreted in urine. Very little is lost via faeces. | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Not highly toxic High doses may cause cyanosis, excitability, diarrhoea |
Handling issues |
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No information available | |||
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Health: H315, H319 | |||
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Not listed (Not listed) | |||
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butaphosphan | ||
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Record last updated: | 13/03/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |