Oxytocin |
Last updated: 20/03/2024 |
(Also known as: endopituitrina; pitocin) |
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A naturally occurring hormone used to manages key aspects of the reproductive system | |
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Not applicable | |
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1906, first identified | |
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Obstetric | |
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Horses, Cattle, Pigs, Sheep, Goats, Dogs, Cats |
Approval status |
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Approved | |
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Approved |
Chemical structure |
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Isomeric | |
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C₄₃H₆₆N₁₂O₁₂S₂ | |
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CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N | |
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CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N | |
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XNOPRXBHLZRZKH-DSZYJQQASA-N | |
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InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1 | |
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Yes |
General status |
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Vasodilator agent | |
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Cyclic nonapeptide hormon | |
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Natural | |
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Substance has a central role in the regulation of parturition and lactation | |
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[Oxytoxinr, Agonist], [Vasopressin receptor, Agonist] | |
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50-56-6 | |
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200-048-4 | |
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439302 | |
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Systemic hormonal preparations; Posterior pituitary lobe hormones | |
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QH01BB02 | |
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No | |
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- | |
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1007.2 | |
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- | |
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide | |
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Current | |
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Formulations |
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Oxytobel Solution for Injection | Bela-Pharm GmbH & Co KG | GB National authorisation | Prescription only medicine to be authorised by a veterinarian (POM-V) | ||||||
Oxytocin | Agilis International Limited, Australia | Not licensed | Not licensed | |||||||
Oxytobel Solution for Injection | MSD Animal health UK Ltd | UK National authorisation | Prescription only medicine to be authorised by a veterinarian (POM-V) | |||||||
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Usually formulated as a solution for injection |
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192 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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93.3 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
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Terrestrial ecotoxicology |
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> 10000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
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Aquatic ecotoxicology |
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General |
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> 10000 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
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Health issues |
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No further information |
Handling issues |
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No information available | |||
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Not listed (Not listed) | |||
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Not regulated | |||
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Shelf-life of the veterinary medicinal product as packaged for sale is approximately18 months, when stored 2-8 DegC. Stable at normal temperatures and pressures. |
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oxytocin | ||
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Record last updated: | 20/03/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |