Temephos (Ref: OMS 786) |
Last updated: 22/08/2024 |
(Also known as: ENT 27165; abaphos; abathion; biothion; difenphos) |
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A nonsystemic organophosphorus insecticide used to control ecoparasites | |
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Current | |
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1965, introduced | |
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Used to control mosquito, midge, and black fly larvae | |
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Sheep; Cats; Dogs |
Approval status |
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Not appproved | |
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Not approved |
Chemical structure |
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None | |
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C₁₆H₂₀O₆P₂S₃ | |
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COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC | |
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- | |
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WWJZWCUNLNYYAU-UHFFFAOYSA-N | |
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InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3 | |
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Yes |
General status |
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Insecticide | |
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Organophosphate insecticide; Organothiophosphate insecticide | |
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- | |
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- | |
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Synthetic | |
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Non-systemic. Acetylcholinesterase (AChE) inhibitor. | |
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[Cholinesterase, Inhibitor] | |
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3383-96-8 | |
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222-191-1 | |
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340 | |
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059001 | |
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5392 | |
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No data found | |
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- | |
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None allocated | |
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No | |
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- | |
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466.47 | |
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O,O,O',O'-tetramethyl O,O'-(sulfanediyldi-4,1-phenylene) bis(phosphorothioate) | |
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O,O,O',O'-tetramethyl O,O'-thiodi-p-phenylene bis(phosphorothioate) | |
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O,O'-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate) | |
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Marine Pollutant; Evidence of use in third world countries; PAN listed Highly Hazardous Chemical | |
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Colourless crystals |
Formulations |
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Coopers Assassin Sheep Dip | Intervet Australia Pty Limited | No GB authorisation for use with animals | Not applicable | ||||||
Stopmos 1G | Ivorychem PTE, Singapore | No GB authorisation for use with animals | Not applicable | |||||||
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0.001 | M4 M = GLEAMS Model database (Groundwater Loading Effects of Agricultural Management Systems). Dataset no longer available. 4 = Verified data |
Low | ||||||||
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9600 | L3 L = Pesticide manuals and hard copy reference books / other sources Hexane3 = Unverified data of known source |
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30.3 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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8.91 X 1004 | Calculated | - | |||||||
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4.95 | G4 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 4 = Verified data |
High | ||||||||
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1.32 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
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9.50 X 10-03 | K4 K = Research datasets (e.g. Pandora, Demetra; these datasets no longer available). Norman Ecotoxicology database. (click here ) 4 = Verified data |
Low volatility | ||||||||
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1.99 X 10-04 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Non-volatile | ||||||||
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Degradation |
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2 | K4 K = Research datasets (e.g. Pandora, Demetra; these datasets no longer available). Norman Ecotoxicology database. (click here ) 4 = Verified data |
Non-persistent | |||||||
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30 | DW4 DW = Don Wauchope personal database for Pka data: Wauchope, R. D. and Edwards, J. Dissociation constants for pesticide active ingredients: a database and comparison with predicted values. Dataset is no longer available. 4 = Verified data |
Moderately persistent | ||||||||
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General literature DT₅₀ approx 2 days (R3) | ||||||||||
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2 | K4 K = Research datasets (e.g. Pandora, Demetra; these datasets no longer available). Norman Ecotoxicology database. (click here ) 4 = Verified data |
Moderately fast | |||||||
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10 | K4 K = Research datasets (e.g. Pandora, Demetra; these datasets no longer available). Norman Ecotoxicology database. (click here ) 4 = Verified data |
Non-persistent | |||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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- | G4 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) 4 = Verified data |
Non-mobile | |||||||
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100000 | ||||||||||
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Fate indices |
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-1.48 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2300 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Whole fish4 = Verified data |
Threshold for concern | |||||||||||||||||||||||||
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Not available | - |
Known soil and groundwater metabolites |
None
Other known metabolites |
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4,4-sulfonyldiphenol | - | Rat (Faecal) | - | ||||
temephos sulfoxide | - | Plant; Rat (Faecal) | - |
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Terrestrial ecotoxicology |
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4204 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Low | ||||||||
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- | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 yr2 = Unverified data of unknown source |
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300 | - | |||||||||
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> 1200 | L3 L = Pesticide manuals and hard copy reference books / other sources Anas platyrhynchos3 = Unverified data of known source |
Moderate | ||||||||
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> 1000 | Q3 Q = Miscellaneous data from online sources Eisenia foetida3 = Unverified data of known source |
Low | ||||||||
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> 1.55 | G4 G = Extension Toxicology network database EXTOXNET. Available online but no longer updated. (click here ) Apis mellifera4 = Verified data |
Moderate | |||||||
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Aquatic ecotoxicology |
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> 3.49 | J4 J = Pesticide Action Network database (click here ) Oncorhynchus mykiss4 = Verified data |
Moderate | ||||||||
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0.00001 | J4 J = Pesticide Action Network database (click here ) Daphnia magna4 = Verified data |
High | ||||||||
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0.0040 | R4 R = Peer reviewed scientific publications Chironomus salinarius 24 hr4 = Verified data |
High | ||||||||
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1.4 | W2 W = French database provided by ARVALIS-Institut du Végétal. Dataset no longer available. Unknown species2 = Unverified data of unknown source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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4204 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
Low | ||||||||
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2181 | L3 L = Pesticide manuals and hard copy reference books / other sources Rabbit3 = Unverified data of known source |
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4.79 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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Intraperitoneal LD₅₀ = 912 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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Subcutaneous LD₅₀ = 912 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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List I; List II | - | - | ||||||||
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Dietary risks from food and drinking water are not of concern due to pattern of use | |||||||||
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Excreted mainly unchanged in the faeces | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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No further information available |
Handling issues |
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Prevent generation of dust and mists IMDG Transport Hazard Class 6.1 |
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Health: H302, H311, H332, H373 Environment: H400, H410 |
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III (Slightly hazardous) | |||
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UN2811 | |||
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Packaging Group III (minor danger) | |||
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Stable and non-reactive under normal conditions of use, storage and transport |
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temephos | ||
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temephos | ||
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Temephos | ||
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temephos | ||
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temefos | ||
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temefos | ||
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temefos | ||
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Record last updated: | 22/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |