Fenobucarb (Ref: BAY 41367C) |

Last updated: 29/08/2025
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(Also known as: BRN 2052332; BPMC) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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Used to control a range of biting and sucking insects in rice and other crops |
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Leaf hoppers, Leaf rollers, Thrips, Stem borers |
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Rice; Cotton |
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- |
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- |
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- |
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Not approved |
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Not applicable |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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Yes |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Fenobucarb is a chiral compound that exhibits optical isomerism due to the presence of a single stereogenic centre in its molecular structure. This chiral centre is located at the carbon atom in the sec-butyl group attached to the aromatic ring, allowing fenobucarb to exist as two distinct enantiomers: (R)-(+)-fenobucarb and (S)-(−)-fenobucarb. Commercial formulations of fenobucarb are typically racemic mixtures. |
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C₁₂H₁₇NO₂ |
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CCC(C)C1=CC=CC=C1OC(=O)NC |
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- |
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DIRFUJHNVNOBMY-UHFFFAOYSA-N |
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InChI=1S/C12H17NO2/c1-4-9(2)10-7-5-6-8-11(10)15-12(14)13-3/h5-9H,4H2,1-3H3,(H,13,14) |
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Yes |
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Insecticide |
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Carbamate insecticide |
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- |
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- |
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Synthetic |
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Contact acting with long residual effects. Acetylcholinesterase (AChE) inhibitor. |
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- |
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- |
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- |
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- |
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- |
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3766-81-2 |
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223-188-8 |
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390 |
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- |
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19588 |
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006-085-00-0 |
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207.27 |
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rac-2-[(2R)-butan-2-yl]phenyl methylcarbamate |
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(RS)-2-sec-butylphenyl methylcarbamate |
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2-(1-methylpropyl)phenyl methylcarbamate |
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- |
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- |
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- |
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Not applicable |
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Not applicable |
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1A |
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Not applicable |
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Nephotettix cincticeps, Sogatella furcifera |
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Oily yellow liquid which may solidify at lower temperatures |
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- |
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1968, introduced |
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- AgroCare
- King Tech Corp
- Sumitomo Chemical Co. Ltd.
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- BayCarb
- Hopcin
- Forcin
- Merlin
- Vitagro
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Available in a variety of formulations including emulsifiable concentrates, dusts, micro granules and ULV liquids. |
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Fenobucarb is synthesised through a multi-step process beginning with 2-sec-butylphenol, which serves as the aromatic backbone. This compound is reacted with triethylamine (Et₃N) as a base, and then slowly combined with the S-methyl ester of N-methylcarbamothioic acid in acetonitrile under reflux conditions over several hours. The reaction mixture is maintained for an extended period, after which the solvent is evaporated under vacuum. The resulting residue is dissolved in dichloromethane, washed sequentially with water, cold sodium hydroxide solution, and brine, then dried over sodium sulphate. |
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Data for the amount of life cycle GHGs produced by fenobucarb are not available in the public domain. However, whilst estimates vary, more general data suggests that between 14 and 19 kilograms of CO₂e is emitted per kilogram of insecticide produced. |
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420.0 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderate |
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- |
- |
- |
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31.5 |
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- |
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Decomposes before boiling |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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- |
- |
- |
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142 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source (closed cup) |
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6.03 X 1002 |
Calculated |
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2.78 |
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Moderate |
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- |
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- |
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- |
- |
- |
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1.04 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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- |
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- |
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48 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Highly volatile. If applied directly to plants or soil, drift is a concern & mitigation is advisable |
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- |
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- |
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18.5 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
Non-persistent |
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- |
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- |
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- |
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General literature DT₅₀ 14-23 Days in upland soil, paddy fields 7-9 days |
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- |
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- |
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6.0 |
R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 2.2-10.9 days, 2 field crops, various matrices, n=4 |
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Stable |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Stable |
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- |
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20 |
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source |
Non-persistent |
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pH sensitive: DT₅₀ 28 days at pH 2, 16.9 days at pH 9, 2 days at pH 10, all at 20 °C |
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- |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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- |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Slightly mobile |
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1068 |
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Estimated |
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- |
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- |
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- |
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- |
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None
Terrestrial ecotoxicology |
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620 |
Rat |
Moderate |
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- |
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- |
- |
- |
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> 2250 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source Colinus virginianus |
Low |
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- |
- |
- |
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- |
- |
- |
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10.7 |
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source Eisenia foetida |
Moderate |
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> 1.70 |
Cyprinus carpio |
Moderate |
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- |
- |
- |
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- |
- |
- |
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0.1 |
Daphnia magna |
Moderate |
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HUMAN HEALTH AND PROTECTION |
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Low (class II) |
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- |
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620 |
Rat |
Moderate |
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5000 |
Rat |
- |
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0.37 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
No data found |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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No further information available |
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IMDG Transport Hazard Class 6,1 |
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Health: H302 Environment: H400, H410 |
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II (Moderately hazardous) |
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UN2991 |
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fenobucarb |
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fenobukarb |
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Record last updated: |
29/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |