Pentacosane |

Last updated: 27/08/2025
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(Also known as: n-pentacosane) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. These hazard alerts do not take account of usage patterns or exposure, thus do not represent risk.
Environmental fate |
Ecotoxicity |
Human health |
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An aliphatic saturated hydrocarbon found in most insects that is used as an attractant for aphid parasitoids |
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Aphids |
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Vegetables |
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Not approved |
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Not applicable |
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No UK approval for use as a plant protection agent |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Pentacosane is isomeric in the broader chemical sense. While n-pentacosane refers specifically to the straight-chain version of the molecule, its formula allows for many structural isomers due to the possibility of branching in the carbon chain. |
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C₂₅H₅₂ |
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CCCCCCCCCCCCCCCCCCCCCCCCC |
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YKNWIILGEFFOPE-UHFFFAOYSA-N |
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InChI=1S/C25H52/c1-3-5-7-9-11-13-15-17-19-21-23-25-24-22-20-18-16-14-12-10-8-6-4-2/h3-25H2,1-2H3 |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
pentacosane |
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Semiochemical; Insecticide |
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Animal-derived substance; Plant-derived substance; Pheromone |
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>97% |
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Natural |
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Contact sex pheromone released by the female of the species and used in traps. Short lived activity. |
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Occurs in beeswax but also found in other natural waxes and some plants including Euphorbia piscatoria and Vanilla madagascariensis |
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Crop protection |
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Aphids |
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Vegetables |
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- |
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629-99-2 |
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211-123-6 |
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None |
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- |
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12406 |
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352.69 |
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- |
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n-pentacosane |
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n-pentacosane |
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- |
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- |
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- |
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Not applicable |
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Not applicable |
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UNM |
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Not applicable |
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- |
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Colourless solid |
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Current |
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early 20th century, discovered |
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- Fine Chemicals
- MP Biomedicals
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Pentacosane is most commonly available in solid form |
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Pentacosane is commercially produced through either fractional distillation of petroleum waxes or extraction from natural sources such as plant essential oils. In the petroleum-based route, high-molecular-weight paraffins are isolated from crude oil refining residues and then subjected to vacuum distillation to separate pentacosane based on its boiling point. For natural extraction, plants like Curcuma longa or Malus domestica are processed using solvent extraction, typically with acetone or hexane, to isolate waxy components, followed by chromatographic purification to obtain high-purity pentacosane. |
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While exact CO₂e values are not published for specific pheromones, some general information is available. The PHERA reported that biotechnological production (e.g. yeast fermentation) of pheromones can reduce GHG emissions by up to 90% compared to traditional chemical synthesis and GHG emissions are typically in the 5 to 10 kg CO₂e per kg of pheromone produced. Other sources suggest that small scale pheromone synthesis typically has emissions in the range 1 – 3 kg CO₂e per kg of pheromone produced. |
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0.005 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
Low |
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54 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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401 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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>230 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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4.17 X 1012 |
Calculated |
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12.62 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
High |
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0.80 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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0.266 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Low volatility. If applied directly to plants, drift is a concern & mitigation is advisable |
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3.77 X 1007 |
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Volatile |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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> 100 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source |
Low |
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> 100 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source Expert judgement |
Low |
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HUMAN HEALTH AND PROTECTION |
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Low (class I) |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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Digestive tract irritant Prevent skin exposure |
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Incompatible with strong oxiding agents |
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Not listed (Not listed) |
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pentacosane |
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Record last updated: |
27/08/2025 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |