Nepetalactone |
Last updated: 26/05/2024
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(Not known by any other names) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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Aromatic bicyclic terpenoid that has insect repellant activity against many insects that is being investigated as a novel plant protection agent. In contrast it is an attractant for cats. |
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Cockroaches; Mosquitoes; Common flies; Aphids |
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Vegetables |
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Current |
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1941, first isolated |
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- |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Isomeric existing in the cis- and trans-forms. Nepetalactone is a name for multiple iridoid analog stereoisomers. |
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C₁₀H₁₄O₂ |
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CC1CCC2C1C(=O)OC=C2C |
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No data |
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ZDKZHVNKFOXMND-UHFFFAOYSA-N |
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InChI=1S/C10H14O2/c1-6-3-4-8-7(2)5-12-10(11)9(6)8/h5-6,8-9H,3-4H2,1-2H3 |
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Yes |
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Insecticide, Semiochemical |
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Plant-derived substance; Pheromone |
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- |
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- |
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Natural |
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Contact action, persistent |
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First iolated from the catnip plant (Nepeta cataria) but also found in the wood of honeysuckle (Lonicera tatarica). Nepetalactones are also produced by many aphids, in which they are sex pheromones. |
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Manufactered for commerical applications |
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Crop protection; Public health |
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Cockroaches; Mosquitoes; Common flies; Aphids |
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Vegetables |
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- |
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490-10-8 |
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- |
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- |
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161367 |
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166.22 |
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- |
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4,7-dimethyl-5,6,7,7a-tetrahydrocyclopenta[c]pyran-1(4aH)-one |
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5,6,7,7a-Tetrahydro-4,7-dimethyl-cyclopenta(c)pyran-1(4ah)-one |
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- |
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- |
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Not applicable |
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Not applicable |
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Not known |
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Not applicable |
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- |
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A colourless oily liquid |
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25 |
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6.46 X 1001 |
Calculated |
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1.81 |
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Low |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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> 1550 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
Moderate |
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> 2000 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source Expert judgement |
Low |
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> 1000 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source Expert judgement |
Low |
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> 100 |
Q2 Q = Miscellaneous data from online sources 2 = Unverified data of unknown source Expert judgement |
Low |
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HUMAN HEALTH AND PROTECTION |
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High (class III) |
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> 1550 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
Moderate |
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Intraperitoneal LD₅₀ = 1550 mg kg⁻¹ |
Mouse |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
XNo, known not to cause a problem |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
XNo, known not to cause a problem |
XNo, known not to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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?Possibly, status not identified |
No data found |
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No further information available |
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No information available |
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Not listed (Not listed) |
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nepetalactone |
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Record last updated: |
26/05/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |