Resveratrol |
Last updated: 25/05/2024
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(Not known by any other names) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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Resveratol is a natural phenol (stilbenoid) deviered from plants that exhibits fungicidal, antiviral and antimicrobial activity |
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Grey mould Botrytis cinerea |
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Cucumber; Grapes |
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Current |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Isomeric. It exists as two geometric isomers: cis- (Z) and trans- (E). |
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C₁₄H₁₂O₃ |
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C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O |
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C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O |
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LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
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InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
trans-resveratrol |
Trans-somer |
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resveratrol |
Unstated isomer |
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Fungicide, Other substance |
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Bactericide, Antimicrobial |
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Plant-derived substance; Phenolic substance |
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Natural |
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Resveratrol is a phytoalexin derived from grapes, peanuts, raspberries, blueberries and other fruits |
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Extracted from the skin of red grapes using a complex multi-step isolation and purification process. However, new biotechnology approaches include using microbial hosts (e.g. Escherichia coli, Saccharomyces cerevisiae, improvising resveratrol biosynthetic genes in them allowing production processes to be improved. |
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Crop protection |
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Grey mould Botrytis cinerea |
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Cucumber; Grapes |
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Suitable for use in all farming systems where approved for use in that country |
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501-36-0 |
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445154 |
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228.24 |
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5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol |
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5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol |
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Not applicable |
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Not applicable |
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Not applicable |
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Not applicable |
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White powdery solid with slight yellow tinge. |
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30.0 |
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Low |
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254 |
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261 |
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1.26 X 1003 |
Calculated |
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3.1 |
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High |
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8.99 |
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pKa(2)=9.63, pKa(3)=10.64 |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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HUMAN HEALTH AND PROTECTION |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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Possible therapeutic benefits for the prevention of inflammatory and neurodegenerative diseasesbut evidence inconclusive, |
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When heated to decomposition it may emit acrid smoke and irritating vapours |
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Not listed (Not listed) |
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resveratrol |
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Record last updated: |
25/05/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |