Diallyl disulfide |
Last updated: 25/05/2024
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(Also known as: garlicin; DAS2) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A major componrnt of garlic extract shown to have insecticidal, fungicidal and other pesticide activity |
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Larval and adult mosquitoes; Other crawling and flying insects; White rot (Sclerotium cepivorum) |
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Onions; Leeks; Ornamentals |
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- |
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- |
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Not commercially available as a pesticide |
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1944, discovered |
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- |
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Not approved |
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Not applicable |
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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None |
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C₆H₁₀S₂ |
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C=CCSSCC=C |
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- |
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PFRGXCVKLLPLIP-UHFFFAOYSA-N |
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InChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2 |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
diallyl disulfide |
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Insecticide, Fungicide, Other substance |
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Antimicrobial |
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Plant-derived substance |
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- |
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- |
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Natural |
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Show to interfere with an insects’ sensory receptors, leading to disorientation and death at all life stages |
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Diallyl disulfide is produced by the decomposition of allicin which is emitted duting the decomposition of Alliaceae plants, especially garlic. It is the main component of the distilled garlic oil. |
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Industrially, diallyl disulfide is produced from sodium disulfide and allyl bromide or allyl chloride at temperatures of 40–60 °C in an inert gas atmosphere |
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Crop protection; General pest management |
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Larval and adult mosquitoes; Other crawling and flying insects; White rot (Sclerotium cepivorum) |
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Onions; Leeks; Ornamentals |
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- |
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2179-57-9 |
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218-548-6 |
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- |
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129087 |
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16590 |
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146.3 |
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3-[(prop-2-en-1-yl)disulfanyl]prop-1-ene |
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3-[(prop-2-en-1-yl)disulfanyl]prop-1-ene |
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- |
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FEMA=2028 |
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- |
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Not applicable |
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Not applicable |
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Not applicable |
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Not applicable |
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- |
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Yellow coloured liquid with strong garlic odour. |
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Alli-Up |
Platte Chemical Co |
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- |
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71.1 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
Moderate |
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176 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
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3.16 X 1003 |
Calculated |
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3.5 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
High |
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1.03 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
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- |
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1.0 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Non-persistent |
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1.0 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data |
Non-persistent |
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General literature: Rapidly breaks down in soil |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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Moderately mobile |
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184 |
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None
Terrestrial ecotoxicology |
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346 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data Rat |
Moderate |
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> 1000 |
P3 P = Other non-EU, UK or US Governments and Regulators 3 = Unverified data of known source Unknown species |
Moderate |
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HUMAN HEALTH AND PROTECTION |
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346 |
P4 P = Other non-EU, UK or US Governments and Regulators 4 = Verified data Rat |
Moderate |
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1967 |
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source Rat |
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Carcinogen |
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Endocrine disruptor |
XNo, known not to cause a problem |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
XNo, known not to cause a problem |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
XNo, known not to cause a problem |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
?Possibly, status not identified |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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Possible irritant May have health benefits - protectant against various cancers and cardiovascular disease May cause respiratory problerms |
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Highly flammable Not explosive or oxidising IMDG Transport Hazard Class 6.1 |
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Health: H226, H301, H315, H319 |
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Not listed (Not listed) |
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UN2810 |
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diallyl disulfide |
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Record last updated: |
25/05/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |