Olaquindox |
Last updated: 10/01/2024 |
(Also known as: olachindox) |
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A quinolone substance with antimicrobial properties | |
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1976, first approval | |
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Used as a growth promotor mainly for pigs. It has also been proved to be effective in control pig dysentery and bacterial enteritis | |
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Pigs; Cattle |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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C₁₂H₁₃N₃O₄ | |
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CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C(=O)NCCO | |
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No data | |
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TURHTASYUMWZCC-UHFFFAOYSA-N | |
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InChI=1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17) | |
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Yes |
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Common Name | Relationship | Link |
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olaquindox | - |
General status |
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Antibiotic, Growth promoter, Performance enhancer, Feed additive | |
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Quinolone | |
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98% | |
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Synthetic | |
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Uncertain but believed to act by suppressing gut bacterial growth | |
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23696-28-8 | |
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245-832-7 | |
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Antiinfectants for systemic use: Antibacterials for systemic use | |
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QJ01MQ01 | |
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No | |
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263.25 | |
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N-(2-hydroxyethyl)-3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-carboxamide | |
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N-(2-hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide | |
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Banned in EU as growth promotor; Evidence of use in third world countries; Not approved as a feed additive in EU | |
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Pale yellow crystals | |
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Formulations |
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202 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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7.41 X 10-03 | Calculated | - | |||||||
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-2.13 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Low | ||||||||
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1.532 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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13.75 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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7.3 | R4 R = Peer reviewed scientific publications 4 = Verified data |
Non-persistent | |||||||
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7.3 | R4 R = Peer reviewed scientific publications 4 = Verified data |
Non-persistent | ||||||||
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DT₅₀ range 5.8-8.8 days | ||||||||||
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7.35 | R4 R = Peer reviewed scientific publications Soil-manure slurry4 = Verified data |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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1.21 | R4 R = Peer reviewed scientific publications 4 = Verified data |
Moderately mobile | |||||||
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88 | ||||||||||
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Literature data Kd range 0.69-1.67 mL g⁻¹, Koc range 46-116 mL g⁻¹, soils=4 | ||||||||||
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1.04 | R4 R = Peer reviewed scientific publications 4 = Verified data |
Moderately mobile | |||||||
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75.6 | ||||||||||
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1.35 | ||||||||||
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Literature data Kf range 0.84-1.20 mL g⁻¹, Kfoc range 56.0-95.5 mL g⁻¹, 1/n range 1.25-1.49, Soils=4 | ||||||||||
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Fate indices |
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1.83 | Calculated | Transition state | ||||||||||||||||||||||||||
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Known soil and groundwater metabolites |
None
Other known metabolites |
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3-methylquinoxaline-2-carboxylic acid | MQCA | Animal | - |
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Terrestrial ecotoxicology |
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1704 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
Moderate | ||||||||
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Aquatic ecotoxicology |
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> 1000 | R3 R = Peer reviewed scientific publications Daphnia magna LOEC3 = Unverified data of known source |
Low | ||||||||
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40 | R4 R = Peer reviewed scientific publications Selenastrum capricornutum4 = Verified data |
Low | ||||||||
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General |
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High (class III) | - | - | ||||||||
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1704 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
Moderate | ||||||||
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> 1.75 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Rat 4 hr4 = Verified data |
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Rapidly absorbed, metabolised and mostly excreted in the urine with lesser amounts in faeces and bile | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Health issues |
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Genotoxic A rodent tumorigen |
Handling issues |
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Emits toxic vapors of NOx when heated to decomposition | |||
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Not listed (Not listed) | |||
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olaquindox | ||
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Record last updated: | 10/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |