Netobimin |
Last updated: 10/01/2024 |
(Not known by any other names) |
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A broad-spectrum pro-benzimidazole veterinary drug | |
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Used to control gastrointestinal infestations of roundworms and tapeworms | |
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Sheep; Goats; Cattle |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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C₁₄H₂₀N₄O₇S₂ | |
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CCCSC1=CC(=C(C=C1)[N+](=O)[O-])NC(=NCCS(=O)(=O)O)NC(=O)OC | |
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No data | |
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WCBVUETZRWGIJQ-UHFFFAOYSA-N | |
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InChI=1S/C14H20N4O7S2/c1-3-7-26-10-4-5-12(18(20)21)11(9-10)16-13(17-14(19)25-2)15-6-8-27(22,23)24/h4-5,9H,3,6-8H2,1-2H3,(H,22,23,24)(H2,15,16,17,19) | |
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Yes |
General status |
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Anthelmintic, Antiparasitic, Medicinal drug, Pro-drug | |
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Carbamate | |
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Synthetic | |
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Metabolised to albendazole which then causes degenerative alterations the parasite cell walls | |
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[Glutamate dehydrogenase enzyme, Inhibitor] | |
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88255-01-0 | |
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Antiparasitic products, insecticides & repellents: Anthelmintics | |
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QP52AC06 | |
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No | |
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Allowed substance [Table 1: Bovine, Ovine] | |
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420.46 | |
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2-(3-methoxycarbonyl-2-(2-nitro-5-propylthiophenyl)guanidino)ethansulfonsaeure | |
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Solid |
Formulations |
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Hapadex Cattle Wormer | Schering-Plough Ltd | Not licensed | Not licensed | ||||||
Hapadex Sheep Wormer | Schering-Plough Ltd | Not licensed | Not licensed | |||||||
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150 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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1.48 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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1.621 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known soil and groundwater metabolites |
None
Other known metabolites |
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albendazole Note: Pharmacologically active |
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albendazole sufoxide | - | - | - | ||||
albendazole sulfone | - | - | - | ||||
albendazole amine sulfone | - | - | - |
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Terrestrial ecotoxicology |
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
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Aquatic ecotoxicology |
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General |
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High (class III) | - | - | ||||||||
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> 5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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Excreted as metabolites in both the urine and the faeces | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Health issues |
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Mutagenic potential Possible liver toxicant |
Handling issues |
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No information available | |||
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Not listed (Not listed) | |||
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netobimin | ||
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netobimine | ||
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netobimina | ||
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Record last updated: | 10/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |