Aminitrozole (Ref: CL 5279) |
Last updated: 20/01/2024 |
(Also known as: nithiamide; 2-acetamido-5-nitrothiazole; nitazole) |
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An obsolete imidazole antibiotic drug | |
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Considered obsolete but may be available in some countries | |
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circa 1960, introduced | |
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Active in vitro against bacteroides, peptococci, peptostreptococci, clostridia, staphylococci, colibacilli and streptococci | |
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Turkeys; Swine |
Approval status |
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Not approved | |
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Not approved |
Chemical structure |
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- | |
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C₅H₅N₃O₃S | |
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CC(=O)NC1=NC=C(S1)[N+](=O)[O-] | |
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- | |
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UJRRDDHEMZLWFI-UHFFFAOYSA-N | |
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InChI=1S/C5H5N3O3S/c1-3(9)7-5-6-2-4(12-5)8(10)11/h2H,1H3,(H,6,7,9) | |
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Yes |
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Common Name | Relationship | Link |
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aminitrozole | - |
General status |
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Antiprotozoal, Antibacterial, Antimicrobial, Medicinal drug | |
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Imidazole | |
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>98% | |
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- | |
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Synthetic | |
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Inhibts microorganism growth | |
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140-40-9 | |
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205-414-7 | |
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8798 | |
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None allocated | |
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No | |
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187.18 | |
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N-(5-nitro-1,3-thiazol-2-yl)acetamide | |
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2-acetylamino-5-nitrothiazole | |
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Yellowish coloured crystalline solid | |
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Formulations |
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1610 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
High | ||||||||
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263 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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304 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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137.5 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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2.00 X 1001 | Calculated | - | |||||||
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1.3 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Low | ||||||||
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1.598 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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0.247 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) 3 = Unverified data of known source |
Low volatility. If applied directly to plants, drift is a concern & mitigation is advisable | ||||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Low risk | Q3 Q = Miscellaneous data from online sources Based on LogP < 33 = Unverified data of known source |
Low risk | |||||||||||||||||||||||||
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 400 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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> 600 | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Meleagris gallopavo3 = Unverified data of known source |
Moderate | ||||||||
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Aquatic ecotoxicology |
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General |
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High (class III) | - | - | ||||||||
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> 400 | Q3 Q = Miscellaneous data from online sources Rat3 = Unverified data of known source |
Moderate | ||||||||
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Intraperitoneal LD₅₀ > 200 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Rat3 = Unverified data of known source |
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Subcutaneous LD₅₀ > 3200 mg kg⁻¹ | V3 V = ChemID Online Databases; Chemspider; PubChem. (ChemID ) Mouse3 = Unverified data of known source |
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Health issues |
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May cause headache, nausea, general malaise & dizuria |
Handling issues |
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May explosively decompose on heating, shock, friction, etc. Light sensitive Do not mix with oxidising compounds |
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Health: H302, H312, H332 | |||
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Not listed (Not listed) | |||
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aminitrozole | ||
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amminitrozol | ||
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amminitrozol | ||
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amminitrozol | ||
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Record last updated: | 20/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |