Imazalil nitrate |
Last updated: 03/03/2024 |
(Also known as: enilconazole nitrate) |
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Toppically applied antifungal agent active against ringworm fungal infections | |
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Current | |
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1977, introduced | |
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Cattle, Horses, Dogs |
Approval status |
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Chemical structure |
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Isomeric | |
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C₁₄H₁₅Cl₂N₃O₄ | |
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C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl.[N+](=O)(O)[O-] | |
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KJTYJTCKKSDSQF-UHFFFAOYSA-N | |
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InChI=1S/C14H14Cl2N2O.HNO3/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16;2-1(3)4/h2-6,8,10,14H,1,7,9H2;(H,2,3,4) | |
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Yes |
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Common Name | Relationship | Link |
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imazalil | Parent |
General status |
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Antifungal agent, Antimycotic | |
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Imidazole fungicide; Conazole fungicide | |
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Synthetic | |
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Systemic with curative and protective properties. Disrupts membrane function. | |
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33586-66-2 | |
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281-012-5 | |
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335 | |
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443088 | |
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No data found | |
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Dermatologicals: Antifungals for dermatological use | |
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QD01AC90 | |
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No | |
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No data | |
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360.19 | |
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(RS)-1-[β-(allyloxy)-2,4-dichlorophenethyl]imidazole nitrate | |
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(RS)-1-[β-(allyloxy)-2,4-dichlorophenethyl]imidazole nitrate | |
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1-[2-(2,4-dichlorophenyl)-2-(2-propen-1-yloxy)ethyl]-1H-imidazole nitrate (1:1) | |
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Formulations |
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Imaverol 100 mg/ml Concentrate for Cutaneous Emulsion | Janssen-Cilag Ltd | No GB authorisation for use with animals, Authorised for use in Ireland | Not applicable | ||||||
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known soil metabolites |
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Minor fraction | - | - | |||||
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Minor fraction | - | - |
Known groundwater metabolites |
None
Other known metabolites |
None
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Terrestrial ecotoxicology |
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Aquatic ecotoxicology |
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General |
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High (class III) | - | - | ||||||||
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0.025 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as imazalil5 = Verified data used for regulatory purposes |
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0.05 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as imazalil5 = Verified data used for regulatory purposes |
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0.05 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as imazalil5 = Verified data used for regulatory purposes |
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No unacceptable risk to bystanders identified Consumers may be exposed via ingestion of contaminated foodstuffs |
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No unacceptable risk for operators or other workers identified | ||||||||||
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Extensively metabolised and the main excretion routes are urine and faeces. | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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Possible liver and kidney toxicant US EPA - probable human carcinogen; CLP data - suspected carcinogen |
Handling issues |
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Not explosive or oxidising IMDG Transport Hazard Class 6.1 Not expected to auto-ignite; Not highly flammable |
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Health: H301, H318, H332. H351 Environment: H410 |
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II (Moderately hazardous) | |||
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UN2811 | |||
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Packaging Group III (minor danger) | |||
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imazalil nitrate | ||
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Record last updated: | 03/03/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |