Tiletamine hydrochloride |
Last updated: 13/01/2024 |
(Not known by any other names) |
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A veterinary anaesthetic which is related chemically to ketamine and commonly used in combination with zolazepam | |
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Current | |
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Anxiety management. Also used to control convulsions and to induce sedation for veterinary surgical procedures | |
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Cats; Dogs; Polar bears |
Approval status |
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Approved | |
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Approved |
Chemical structure |
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Racemic. 1 stereocentre | |
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C₁₂H₁₈ClNOS | |
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CCNC1(CCCCC1=O)C2=CC=CS2.Cl | |
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ZUYKJZQOPXDNOK-UHFFFAOYSA-N | |
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InChI=1S/C12H17NOS.ClH/c1-2-13-12(11-7-5-9-15-11)8-4-3-6-10(12)14;/h5,7,9,13H,2-4,6,8H2,1H3;1H | |
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Yes |
General status |
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Medicinal drug, Anaesthetic, Sedative | |
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Unclassified medicinal drug | |
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Synthetic | |
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NMDA receptor antagonist. It generates a so-called dissociative anaesthesia because it depresses certain cerebral regions whilst other regions, in particular the limbic system, remain active. | |
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[NMDA receptor, Antagonist] | |
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14176-50-2 | |
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604-248-6 | |
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26543 | |
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Nervous system: Other general anaesthetics | |
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QN02AX99 | |
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No | |
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259.8 | |
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2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one;hydrochloride | |
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2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one;hydrochloride | |
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White crystalline solid | |
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Formulations |
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Zoletil 100 Injection for dogs & cats | Virbac | GB National authorisation | Prescription only medicine to be authorised by a veterinarian (POM-V) | ||||||
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Usually formulated as a solution for injection |
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20000 | Q3 Q = Miscellaneous data from online sources Ethanol3 = Unverified data of known source |
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186 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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352.6 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Fate indices |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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160 | Q3 Q = Miscellaneous data from online sources Mouse3 = Unverified data of known source |
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General |
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160 | Q3 Q = Miscellaneous data from online sources Mouse3 = Unverified data of known source |
Moderate | ||||||||
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Metabolised in the liver, excreted via the kidneys | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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Health issues |
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May cause drowsiness |
Handling issues |
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IMDG Transport Hazard Code 6.1 | |||
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Health: H301, H361, H336 | |||
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Not listed (Not listed) | |||
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UN2811 | |||
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Packaging group III (minor danger) | |||
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tiletamine hydrochloride | ||
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Record last updated: | 13/01/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |