(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
Last updated: 21/05/2024
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(Also known as: DMDP; NSC 624987) |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate |
Ecotoxicity |
Human health |
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A naturally occurring sugar anologue that has nematicide activity currently being explored for its potential as a biocontrol agent |
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Soil-borne nematodes |
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Vegetables; Bananas; Coffee; Cotton; Tobacco |
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Current |
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Not approved |
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Not applicable |
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Not applicable |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved |
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Not applicable |
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Not applicable |
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Not applicable |
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No |
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ATAustria |
BEBelgium |
BGBulgaria |
CYCyprus |
CZCzech Republic |
DEGermany |
DKDenmark |
EEEstonia |
ELGreece |
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ESSpain |
FIFinland |
FRFrance |
HRCroatia |
HUHungary |
IEIreland |
ITItaly |
LTLithuania |
LULuxembourg |
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LVLatvia |
MTMalta |
NLNetherlands |
PLPoland |
PTPortugal |
RORomania |
SESweden |
SISlovenia |
SKSlovakia |
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ISIceland |
NONorway |
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Isomeric |
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C₆H₁₃NO₄ |
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C(C1C(C(C(N1)CO)O)O)O |
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C([C@@H]1[C@H]([C@@H]([C@H](N1)CO)O)O)O |
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PFYHYHZGDNWFIF-KVTDHHQDSA-N |
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InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1 |
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Yes |
Cambridge Crystallographic Data Centre diagrams |
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Common Name |
Relationship |
Link |
(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
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Insecticide, Nematicide |
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Plant-derived substance |
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May contain traces of rotenone |
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Natural |
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Unclear but thought to relate to glycosidase inhibition |
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Isolated from tropical legumes including Lancepods (Lonchocarpus spp.) and Derris) spp. |
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Some extracted direct from the plant but now largely synthesised for commercial supply |
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Crop protection |
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Soil-borne nematodes |
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Vegetables; Bananas; Coffee; Cotton; Tobacco |
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59920-31-9 |
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232-889-8 |
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163.17 |
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2,5-dideoxy-2,5imino-D-mannitol |
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(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
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Not applicable |
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Not applicable |
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Not known |
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Not applicable |
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- |
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Off-white coloured solid |
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Usually formulated for application as a foliar spray |
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102 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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220 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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1.408 |
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. |
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Soil adsorption and mobility |
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None
Terrestrial ecotoxicology |
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HUMAN HEALTH AND PROTECTION |
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High (class III) |
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Carcinogen |
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Endocrine disruptor |
No data found |
A0 A = Chromosome aberration (EFSA database) 0 = No data ; B0 B = DNA damage/repair (EFSA database) 0 = No data ; C0 C = Gene mutation (EFSA database) 0 = No data ; D0 D = Genome mutation (EFSA database) 0 = No data ; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data |
No data found |
Reproduction / development effects |
Acetyl cholinesterase inhibitor |
Neurotoxicant |
No data found |
No data found |
No data found |
Respiratory tract irritant |
Skin irritant |
Skin sensitiser |
✓Yes, known to cause a problem |
✓Yes, known to cause a problem |
No data found |
Eye irritant |
Phototoxicant |
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✓Yes, known to cause a problem |
No data found |
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No information available |
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No information available |
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Not listed (Not listed) |
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(2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine |
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Record last updated: |
21/05/2024 |
Contact: |
aeru@herts.ac.uk |
Please cite as: |
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |