L-carvone (Ref: L 91105D) |
Last updated: 24/07/2024 |
(Also known as: p-mentha-6,8-dien-2-one; R-carvone; spearment oil component; (-)-carvone) |
SUMMARY |
L-carvone is a plant-derived pesticide that is approved for use in many countries. It has a low aqueous solubility and is volatile. There is limited data availablity regarding its persistent in soil andwater systems. It has a low mammalian oral toxicity and is a recognised irritant. Ecotoxicity tends to be low to moderate for most species. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A fungicide and plant growth regulator often used as a potato sprouting inhibitor | |
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Sprout growth | |
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Seed potatoes | |
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Authorised for use and widely used for over 10 years | |
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Current | |
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2009, registered in EU | |
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UK regulatory status |
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Approved (as carvone) | ||
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31/07/2034 | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Pending | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Sweden | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Chemical structure |
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A chiral molecule existing in the R- and S- enantiomers. L-carvone refers to the R-form. | |
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C₁₀H₁₄O | |
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CC1=CCC(CC1=O)C(=C)C | |
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CC1=CC[C@H](CC1=O)C(=C)C | |
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ULDHMXUKGWMISQ-SECBINFHSA-N | |
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InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9H,1,5-6H2,2-3H3 | |
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Yes |
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Common Name | Relationship | Link |
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L-carvone | - |
General status |
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Plant Growth Regulator, Metabolite | |
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Soil, Groundwater | |
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Plant-derived substance | |
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>930g kg⁻¹ | |
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- | |
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Natural | |
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Inhibits cell growth | |
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Carvone is found naturally in many essential oils including spearmint (Mentha spicata) and can also be found in caraway and dill seeds | |
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Produced commercially for agriculture | |
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Post harvest management | |
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None - PGR | |
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Potatoes | |
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Suitable for use in all farming systems where approved for use in that country | |
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6485-40-1 | |
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229-352-5 | |
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602 | |
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- | |
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- | |
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150.21 | |
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- | |
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(R)-5-isopropenyl-2-methylcyclohex-2-en-1-one | |
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(R)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one | |
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- | |
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- | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Not applicable | |
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Colourless to pale yellow liquid | |
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Can be a metabolite of: |
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QRD-460 Terpenoid blend | Soil | - | - | |||||
orange oil | Soil | - | - |
Formulations |
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Xeda Bio | Xeda International | ||||
Xeda HM Nat | Xeda International | |||||
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Usually supplied in formulations for hot or cold fogging for indoor use only |
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27 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Xylene5 = Verified data used for regulatory purposes |
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250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Heptane5 = Verified data used for regulatory purposes |
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25000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
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250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
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-43 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Freezing point5 = Verified data used for regulatory purposes |
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233 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as Carvone4 = Verified data |
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98 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as Carvone5 = Verified data used for regulatory purposes |
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2.51 X 1002 | Calculated | - | |||||||
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2.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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0.957 | Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source |
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1900 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as Carvone5 = Verified data used for regulatory purposes |
Highly volatile. If applied directly to plants or soil, drift is a concern & mitigation is advisable | ||||||||
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3.6 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) as Carvone5 = Verified data used for regulatory purposes |
Moderately volatile | ||||||||
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57.2 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Known metabolites |
None
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Terrestrial ecotoxicology |
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> 2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as Carvone5 = Verified data used for regulatory purposes |
Low | ||||||||
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> 1000 | Q2 Q = Miscellaneous data from online sources Expert judgement2 = Unverified data of unknown source |
Low | ||||||||
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100 | Q2 Q = Miscellaneous data from online sources Expert judgement2 = Unverified data of unknown source |
Moderate | ||||||||
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Aquatic ecotoxicology |
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> 20.3 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss3 = Unverified data of known source |
Moderate | ||||||||
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58.2 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio Embryo3 = Unverified data of known source |
Moderate | ||||||||
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> 9.59 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna3 = Unverified data of known source |
Moderate | ||||||||
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4.58 | A3 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Unknown species3 = Unverified data of known source |
Moderate | ||||||||
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General |
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Intermediate (class II) | - | - | ||||||||
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> 2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as Carvone5 = Verified data used for regulatory purposes |
Low | ||||||||
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4000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat as Carvone5 = Verified data used for regulatory purposes |
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> 5.66 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat 4 hr as Carvone5 = Verified data used for regulatory purposes |
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0.025 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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None allocated | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.025 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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PPE/PPC recommended | ||||||||||
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Health issues |
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May cause gastrointestinal tract irritation with nausea, vomiting and diarrhoea Skin sensitiser Possible kidney toxicant Strong antiseptic properties |
Handling issues |
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Not explosve or oxidising Flammable |
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Health: H317 | |||
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Not listed (Not listed) | |||
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L-carvone | ||
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l-carvone | ||
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l-Carvon | ||
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l-carvon | ||
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l-carvone | ||
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l-carvone | ||
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L-karwon | ||
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Record last updated: | 24/07/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |